Human IDH ELISA Kit

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SKU:
HUFI01071
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
O75874
Sensitivity:
46.875pg/ml
Range:
78.125-5000pg/ml
ELISA Type:
Sandwich
Synonyms:
IDH1, IsocitRate dehydrogenase [NADP] cytoplasmic, Oxalosuccinate decarboxylase, NADP, +-specific ICDH, IDH, Cytosolic NADP-isocitRate dehydrogenase, IDP, PICD, IDCD, IDPC
Reactivity:
Human
Research Area:
Metabolism

Description

Human IDH ELISA Kit

The oxidative decarboxylation of isocitrate to 2-oxoglutarate is catalysed by isocitrate dehydrogenases. These enzymes are divided into two groups, one that uses NAD(+) as an electron acceptor and the other that uses NADP(+). Three NAD(+)-dependent isocitrate dehydrogenases that localise to the mitochondrial matrix have been identified, as well as two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each isozyme that is dependent on NADP(+) is a homodimer. The NADP(+)-dependent isocitrate dehydrogenase found in the cytoplasm and peroxisomes is encoded by this gene. Metaphyseal Enchondromatosis With D-2-Hydroxyglutaric Aciduria and Glioma Susceptibility 1 are two diseases linked to IDH1. Amino Acid Metabolism and HIV Life Cycle are two related pathways.

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