Human ICOSLG (ICOS ligand) ELISA Kit (HUFI05147)

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SKU:
HUFI05147
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
O75144
Sensitivity:
0.094ng/ml
Range:
0.156-10ng/ml
ELISA Type:
Sandwich
Synonyms:
ICOS ligand, B7 homolog 2, Short name:, B7-H2, B7-like protein Gl50, B7-related protein 1, B7RP-1, CD275
Reactivity:
Human

Description

Human ICOSLG (ICOS ligand) ELISA

ICOSLG (ICOS ligand), also known as CD275, is a glycosylated transmembrane structure belonging to the B7 family. During secondary immune responses, the interaction of ICOSLG with its unique receptor ICOS is essential in the activation, proliferation, differentiation, and cytokine production of T cells as well as antibody secretion from B cells. ICOSLG is highly expressed in non-lymphatic and lymphatic tissues, and can be induced by IFN-?, TNF-?, or LPS stimulation. The ICOS/ICOSLG pathway is linked to immunopathogenesis, such as infection, hypersensitivity, organ transplantation immunity and autoimmune disorders.

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