Human HSF4 ELISA Kit

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SKU:
HUFI02070
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
Q9ULV5
Sensitivity:
0.094ng/ml
Range:
0.156-10ng/ml
ELISA Type:
Sandwich
Synonyms:
HSF4, ATHSF4, AT-HSFB1, CTM, HSFB1, cataract, Marner, heat shock factor protein 4, heat shock transcription factor 4CTM, hHSF4, HSF 4, HSTF 4
Reactivity:
Human
Research Area:
Metabolism

Description

Human HSF4 ELISA

HSF4 (Heat Shock Transcription Factor 4) encodes a heat shock transcription factor which binds to the heat shock element (HSE) in promoter regions of Hsp70-encoding genes, as well as to GADD153, which is induced during stress conditions including heat shock or hypoxia/anoxia. Heat shock elements can be found upstream or downstream from DNA segments encoding for protein synthesis machinery parts such as ribosomes, RNA polymerase II promoters. Diseases associated with HSF4 include lissencephaly, microcephalic primordial dwarfism, and tuberous sclerosis. An important paralog of HSF4 is HSF1.

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