Human HSCB Recombinant Protein (RPPB3720)

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RPPB3720

Description

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Product Name:Human HSCB Recombinant Protein
Product Code:RPPB3720
Size:20µg
Species:Human
Target:HSCB
Synonyms:HscB iron-sulfur cluster co-chaperone homolog (E. coli), DnaJ homolog (Hsp40) subfamily C member 20, iron-sulfur cluster co-chaperone protein HscB mitochondrial, J-type co-chaperone HSC20, DNAJC20, HSC20, dJ366L4.2, JAC1.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered colorless solution.
Formulation:The HSCB solution (1mg/1ml) contains 20mM Tris-HCl buffer (pH 8.0), 150mM NaCl, and 10% glycerol.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 90% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MGSHMAASQA GSNYPRCWNC GGPWGPGRED RFFCPQCRAL QAPDPTRDYF SLMDCNRSFR VDTAKLQHRY QQLQRLVHPD FFSQRSQTEK DFSEKHSTLV NDAYKTLLAP LSRGLYLLKL HGIEIPERTD YEMDRQFLIE IMEINEKLAE AESEAAMKEI ESIVKAKQKE FTDNVSSAFE QDDFEEAKEI LTKMRYFSNI EEKIKLKKIP L

HscB Iron-Sulfur Cluster Co-Chaperone (HSCB) is a member of the hscB family and contains 1 J domain. HSCB is expressed in the lung, brain, stomach, spleen, ovary, testis, liver, muscle and heart and localized to mitochondria and cytoplasm. HSCB may function as a co-chaperone in iron-sulfur cluster assembly in mitochondria, it also interacts with ISCU and HSPA9.

HSCB Human Recombinant produced in E. coli is a single polypeptide chain containing 231 amino acids (30-235) and having a molecular mass of 26.7 kDa.HSCB is fused to a 25 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

UniProt Protein Function:HSCB: Acts as a co-chaperone in iron-sulfur cluster assembly in mitochondria. Belongs to the HscB family.
UniProt Protein Details:

Protein type:Mitochondrial; Chaperone

Chromosomal Location of Human Ortholog: 22q12.1

Cellular Component: centrosome; mitochondrion; cytoplasm; plasma membrane

Molecular Function:protein binding; chaperone binding; metal ion binding

Biological Process: protein folding; iron-sulfur cluster assembly; protein oligomerization

UniProt Code:Q8IWL3
NCBI GenInfo Identifier:50301234
NCBI Gene ID:150274
NCBI Accession:NP_741999.3
UniProt Secondary Accession:Q8IWL3,Q9BWS7,
UniProt Related Accession:Q8IWL3
Molecular Weight:27,422 Da
NCBI Full Name:iron-sulfur cluster co-chaperone protein HscB, mitochondrial
NCBI Synonym Full Names:HscB mitochondrial iron-sulfur cluster co-chaperone
NCBI Official Symbol:HSCB��
NCBI Official Synonym Symbols:JAC1; HSC20; DNAJC20; dJ366L4.2��
NCBI Protein Information:iron-sulfur cluster co-chaperone protein HscB, mitochondrial; DnaJ (Hsp40) homolog, subfamily C, member 20; HscB iron-sulfur cluster co-chaperone homolog; J-type co-chaperone HSC20; dnaJ homolog subfamily C member 20
UniProt Protein Name:Iron-sulfur cluster co-chaperone protein HscB, mitochondrial
UniProt Synonym Protein Names:DnaJ homolog subfamily C member 20; Hsc20
Protein Family:Co-chaperone protein
UniProt Gene Name:HSCB��
UniProt Entry Name:HSC20_HUMAN
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Additional Information

Product Type:
Recombinant Protein
Species:
Human
Uniprot:
Q8IWL3
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