Human HSCB Recombinant Protein (RPPB3720)
- SKU:
- RPPB3720
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- Q8IWL3
Description
| Product Name: | Human HSCB Recombinant Protein |
| Product Code: | RPPB3720 |
| Size: | 20µg |
| Species: | Human |
| Target: | HSCB |
| Synonyms: | HscB iron-sulfur cluster co-chaperone homolog (E. coli), DnaJ homolog (Hsp40) subfamily C member 20, iron-sulfur cluster co-chaperone protein HscB mitochondrial, J-type co-chaperone HSC20, DNAJC20, HSC20, dJ366L4.2, JAC1. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | The HSCB solution (1mg/1ml) contains 20mM Tris-HCl buffer (pH 8.0), 150mM NaCl, and 10% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 90% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSHMAASQA GSNYPRCWNC GGPWGPGRED RFFCPQCRAL QAPDPTRDYF SLMDCNRSFR VDTAKLQHRY QQLQRLVHPD FFSQRSQTEK DFSEKHSTLV NDAYKTLLAP LSRGLYLLKL HGIEIPERTD YEMDRQFLIE IMEINEKLAE AESEAAMKEI ESIVKAKQKE FTDNVSSAFE QDDFEEAKEI LTKMRYFSNI EEKIKLKKIP L |
HscB Iron-Sulfur Cluster Co-Chaperone (HSCB) is a member of the hscB family and contains 1 J domain. HSCB is expressed in the lung, brain, stomach, spleen, ovary, testis, liver, muscle and heart and localized to mitochondria and cytoplasm. HSCB may function as a co-chaperone in iron-sulfur cluster assembly in mitochondria, it also interacts with ISCU and HSPA9.
HSCB Human Recombinant produced in E. coli is a single polypeptide chain containing 231 amino acids (30-235) and having a molecular mass of 26.7 kDa.HSCB is fused to a 25 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | HSCB: Acts as a co-chaperone in iron-sulfur cluster assembly in mitochondria. Belongs to the HscB family. |
| UniProt Protein Details: | Protein type:Mitochondrial; Chaperone Chromosomal Location of Human Ortholog: 22q12.1 Cellular Component: centrosome; mitochondrion; cytoplasm; plasma membrane Molecular Function:protein binding; chaperone binding; metal ion binding Biological Process: protein folding; iron-sulfur cluster assembly; protein oligomerization |
| UniProt Code: | Q8IWL3 |
| NCBI GenInfo Identifier: | 50301234 |
| NCBI Gene ID: | 150274 |
| NCBI Accession: | NP_741999.3 |
| UniProt Secondary Accession: | Q8IWL3,Q9BWS7, |
| UniProt Related Accession: | Q8IWL3 |
| Molecular Weight: | 27,422 Da |
| NCBI Full Name: | iron-sulfur cluster co-chaperone protein HscB, mitochondrial |
| NCBI Synonym Full Names: | HscB mitochondrial iron-sulfur cluster co-chaperone |
| NCBI Official Symbol: | HSCB�� |
| NCBI Official Synonym Symbols: | JAC1; HSC20; DNAJC20; dJ366L4.2�� |
| NCBI Protein Information: | iron-sulfur cluster co-chaperone protein HscB, mitochondrial; DnaJ (Hsp40) homolog, subfamily C, member 20; HscB iron-sulfur cluster co-chaperone homolog; J-type co-chaperone HSC20; dnaJ homolog subfamily C member 20 |
| UniProt Protein Name: | Iron-sulfur cluster co-chaperone protein HscB, mitochondrial |
| UniProt Synonym Protein Names: | DnaJ homolog subfamily C member 20; Hsc20 |
| Protein Family: | Co-chaperone protein |
| UniProt Gene Name: | HSCB�� |
| UniProt Entry Name: | HSC20_HUMAN |
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