Human HRH3 Full-Length Bioactive Membrane Protein (HDFP114)

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SKU:
HDFP114
Product Type:
Recombinant Protein
Protein Type:
Full-Length Bioactive Membrane Protein
Species:
Human
Uniprot:
Q9Y5N1

Description

system_update_altDatasheet
Product nameHuman HRH3 full length protein-synthetic nanodisc
Size:10ug
Product SKU:HDFP114
Product CategoryFull Length Transmembrane Proteins
Target:HRH3
Uniprot:Q9Y5N1
Description:Human HRH3 full length protein-synthetic nanodisc
Molecular Weight:The human full length HRH3 protein has a MW of 48.5 kDa
Protein Family:Druggable Genome, Transmembrane
Protein Pathways:Neuroactive ligand-receptor interaction
Storage & Shipping:Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Synonyms:GPCR97; HH3R
Expression System:HEK293
Formulation:Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions.
Background:Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. This gene encodes one of the histamine receptors (H3) which belongs to the family 1 of G protein-coupled receptors. It is an integral membrane protein and can regulate neurotransmitter release. This receptor can also increase voltage-dependent calcium current in smooth muscles and innervates the blood vessels and the heart in cardiovascular system. [provided by RefSeq, Jul 2008]
Delivery:3-4 weeks
UsageResearch use only
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