Description
| Product Name: | Human HN1 Recombinant Protein |
| Product Code: | RPPB3703 |
| Size: | 10µg |
| Species: | Human |
| Target: | HN1 |
| Synonyms: | ARM2, HN1A, Hematological and neurological expressed 1 protein, Androgen-regulated protein 2, HN1. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | The HN1 solution (0.5mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.1M NaCl and 10% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 90% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MTTTTTFKGV DPNSRNSSRV LRPPGGGSNF SLGFDEPTEQ PVRKNKMASN IFGTPEENQA SWAKSAGAKS SGGREDLESS GLQRRNSSEA SSGDFLDLKG EGDIHENVDT DLPGSLGQSE EKPVPAAPVP SPVAPAPVPS RRNPPGGKSS LVLG |
Hematological and neurological expressed 1 protein (HN1) is a small protein which is extremely preserved among species. HN1 expression is upregulated in regenerating neural tissues, including the axotomized adult rodent facial motor nerve and dedifferentiating retinal pigment epithelial cells of the Japanese newt. HN1 is also expressed in several tissues during embryonic development as well as in regions of the adult brain which display high plasticity.
HN1 Human Recombinant produced in E. coli is a single polypeptide chain containing 174 amino acids (1-154) and having a molecular mass of 18.1kDa. HN1 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | HN1: a nuclear protein of the HN1 family. Upregulated in advanced-stage epithelial ovarian cancer. Three alternatively spliced isoforms have been described. |
| UniProt Protein Details: | Protein type:Unknown function Chromosomal Location of Human Ortholog: 17q25.1 Cellular Component: nucleus Biological Process: developmental process |
| UniProt Code: | Q9UK76 |
| NCBI GenInfo Identifier: | 74735046 |
| NCBI Gene ID: | 51155 |
| NCBI Accession: | Q9UK76.3 |
| UniProt Secondary Accession: | Q9UK76,Q53FG7, Q7Z2D2, Q7Z2F0, B2R6K3, |
| UniProt Related Accession: | Q9UK76 |
| Molecular Weight: | 154 |
| NCBI Full Name: | Hematological and neurological expressed 1 protein |
| NCBI Synonym Full Names: | hematological and neurological expressed 1 |
| NCBI Official Symbol: | HN1�� |
| NCBI Official Synonym Symbols: | ARM2; HN1A�� |
| NCBI Protein Information: | hematological and neurological expressed 1 protein; androgen-regulated protein 2 |
| UniProt Protein Name: | Hematological and neurological expressed 1 protein |
| UniProt Synonym Protein Names: | Androgen-regulated protein 2Hematological and neurological expressed 1 protein, N-terminally processed |
| Protein Family: | Hematological and neurological expressed 1 protein |
| UniProt Gene Name: | HN1�� |
| UniProt Entry Name: | HN1_HUMAN |
