Immunology Recombinant Proteins

Human HMGB1 Recombinant Protein (RPES2218)

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SKU:
RPES2218
Product Type:
Recombinant Protein
Species:
Human
Research Area:
Immunology

Description

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Human HMGB1 Recombinant Protein

B1 is a member of the HMGB family, which includes three other proteins: HMGB1, HMGB2, and HMGB3. It includes two HMG box DNA-binding domains - box A and B, which are highly negatively charged at their C termini. HMGB1 is a nuclear protein that maintains nucleosomes and permits DNA bending, which is required for gene transcription. Finally, it is shown that HMGB1 can also function as a cytokine extracellularly and regulate monocyte, T cell, dendritic cell activities in inflammatory responses. Human HMGB1 Recombinant Protein is a highly pure recombinant protein developed by Assay Genie for use in a range of applications.

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