Description
| Product Name: | Human HLA-A*0201 HPV16 E7 complex Recombinant Protein (C-10His) |
| Product Code: | RPES6395 |
| Size: | 10µg |
| Species: | Human |
| Expression Host: | HEK293 Cells |
| Mol Mass: | 49.1 kDa |
| AP Mol Mass: | 55-60 kDa |
| Tag: | C-10His |
| Purity: | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin Level: | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Bio Activity: | Testing in progress |
| Sequence: | YMLDLQPET&Ile21-Met119&Gly25-Ile308 (Ala269Val) |
| Accession: | P61769&P01892 |
| Storage: | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation: | Lyophilized from a 0.2 μm filtered solution of 20mM PB, 500mM NaCl, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed man |
| Reconstitution: | Please refer to the printed manual for detailed information. |
| Background: | The HPV16 E7 protein plays a role in viral genome replication by driving entry of quiescent cells into the cell cycle. E7 protein has both transforming and trans-activating activities. It plays also a role in the inhibition of both antiviral and antiproliferative functions of host interferon alpha. |