Human HIG2 ELISA Kit

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SKU:
HUFI01801
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
Q9Y5L2
Sensitivity:
0.375ng/ml
Range:
0.625-40ng/ml
ELISA Type:
Sandwich
Synonyms:
HIG2, C7orf68, FLJ21076, HIG-2, HIG2.
Reactivity:
Human
Research Area:
Metabolism

Description

Human HIG2 ELISA

HIG2 is a transcription regulator that is encoded by the HIBAG gene (High-mobility group AT-hook 2). HIG2 can associate with heterochromatin via its interaction with HP1alpha. High HIG2 expression is found in embryonic stem cells, testis and in tumors. HIG2 controls the expression of numerous genes by recruiting histone-modifying enzymes to specific promoters. HIG2 protein is highly expressed in tumors, along with the chromatin modifiers DNMT3a and TET1, suggesting that it may play a role in cancer by reprogramming DNA methylation patterns. Diseases associated with HIG2 are Smith–Magenis syndrome and colorectal cancer.

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