Human HERPUD1 ELISA Kit

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SKU:
HUFI01048
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
Q15011
Sensitivity:
0.094ng/ml
Range:
0.156-10ng/ml
ELISA Type:
Sandwich
Synonyms:
HERPUD1, HERP, KIAA0025, MIF1, Methyl methanesulfonate, MMF-inducible fragment protein 1
Reactivity:
Human
Research Area:
Signal Transduction

Description

Human HERPUD1 ELISA Kit

The ER stress response is triggered by an accumulation of unfolded proteins in the endoplasmic reticulum (ER). The unfolded protein response (UPR) includes the inhibition of translation to prevent the accumulation of more unfolded proteins, and the ER-associated protein degradation (ERAD) system, which includes the increased expression of proteins involved in polypeptide folding. Both UPR and ERAD may be affected by HERPUD1. HERPUD1 has an ER stress response element in its promoter region, and the encoded protein has an N-terminal ubiquitin-like domain that may interact with the ERAD system. Its expression is induced by UPR, and it has an ER stress response element in its promoter region. Hereditary Breast Ovarian Cancer Syndrome and Phacolytic Glaucoma are two diseases linked to HERPUD1.

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