Human Hepsin ELISA Kit

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SKU:
HUFI01651
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
P05981
Sensitivity:
0.469ng/ml
Range:
0.781-50ng/ml
ELISA Type:
Sandwich
Synonyms:
HPN, TMPRSS1, hepsin, serine protease hepsin, serine protease hepsin catalytic chain, serine protease hepsin non-catalytic chain, Transmembrane protease serine 1, transmembrane protease, serine 1
Reactivity:
Human

Description

Human Hepsin ELISA

HPN (Hepsin) is a serine protease that is overexpressed in many types of cancer, including pancreatic cancer. HPN encodes a type II transmembrane serine protease that may be involved in diverse cellular functions, including blood coagulation and the maintenance of cell morphologyHPN has been shown to promote tumor cell proliferation and invasion, and to suppress the antitumor immune response. Diseases associated with HPN include Prostate Cancer and Prostatic Hyperplasia, Benign. Among HPN related pathways are Signaling by GPCR and MET promotes cell motility. An important paralog of HPN is TMPRSS3.

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