Human HBP1 ELISA Kit

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SKU:
HUFI02001
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
O60381
Sensitivity:
0.094ng/ml
Range:
0.156-10ng/ml
ELISA Type:
Sandwich
Synonyms:
HBP1, HMG box transcription factor 1, High mobility group box transcription factor 1,
Reactivity:
Human
Research Area:
Epigenetics and Nuclear Signaling

Description

Human HBP1 ELISA

HBP1 (HMG-Box Transcription Factor 1) is the key transcription factor for cellular differentiation. HBP1 regulates major metabolic pathways in all tissues by coordinating gene expression networks to maintain stem cell pluripotency and specialization of various cells, thus determining their fate. HBP1 is not only central to cell cycle progression but also performs tissue-specific functions including self renewal, proliferation, survival, differentiation and cell death. Aberrant regulation of HBP1 results in a wide range of cancers, thus making it a prime target for cancer therapeutics. Mutations that cause an increase or decrease in HBP1 expression have been associated with metabolic diseases including obesity and diabetes.

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