Hydroxyacid Oxidase 1 (HAO1) is an enzyme that belongs to the FMN-Dependent ?-Hydroxy Acid Dehydrogenase family. HAO1 contains 1 FMN Hydroxy Ccid Dehydrogenase domain. HAO1 is expressed primarily in the liver and pancreas. This protein has 2-Hydroxyacid Oxidase activity. Most HAO1 is active on the 2-Carbon substrate Glycolate; but it can also be active on 2-Hydroxy fatty acids; with higher activity towards 2-Hydroxy Palmitate and 2-Hydroxy Octanoate.
Recombinant Human Hydroxyacid Oxidase 1 is produced by our E.coli expression system and the target gene encoding Met1-Ile370 is expressed with a Trx; 6His tag at the N-terminus.
Purity:
> 95 % as determined by reducing SDS-PAGE.
Mol Mass:
58.6 kDa
AP Mol Mass:
56 kDa
Formulation:
Supplied as a 0.2 µm filtered solution of 20mM PB; 150mM NaCl; pH 7.2.
Shipping:
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt; store it immediately at<-20°C.
Stability and Storage:
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.