Human GSTA3 / Glutathione S-transferase A3 ELISA Kit

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SKU:
HUFI01601
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
Q16772
Sensitivity:
0.188ng/ml
Range:
0.313-20ng/ml
ELISA Type:
Sandwich
Synonyms:
GSTA3, Glutathione S-transferase A3, GST class-alpha member 3, Glutathione S-transferase A3-3
Reactivity:
Human

Description

Human GSTA3 / Glutathione S-transferase A3 ELISA

GSTA3 (Glutathione S-Transferase Alpha 3) is an enzyme located on chromosome 5 which controls the cellular detoxification of electrophilic molecules. The GSTA3 gene 's level of expression was found to be significantly reduced in cancer tissue versus normal tissue, leading researchers to believe that it may play a role in tumor suppression. In addition, since glutathione is a cofactor in the reaction catalyzed by GSTA3, lower levels of glutathione in the cell may also contribute to tumor formation. GSTA3 has been proposed as a biomarker of colorectal cancer. Diseases associated with GSTA3 include Enchondromatosis, Multiple, Ollier Type and Seminal Vesicle Tumor.

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