Metabolism Recombinant Proteins

Human GSS Recombinant Protein (RPES5105)

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RPES5105

Description

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Human GSS Recombinant Protein

Glutathione Synthetase belongs to the eukaryotic GSH synthase family. Glutathione Synthetase is the second enzyme in the glutathione biosynthesis pathway. It catalyses the condensation of gamma-glutamylcysteine and glycine to form glutathione. Glutathione play an important role in a variety of biological functions, including detoxification of xenobiotics, protection of cells from oxidative damage by free radicals, and membrane transport. The protein functions as a homodimer to catalyze the second step of glutathione biosynthesis, which is the ATP-dependent conversion of gamma-L-glutamyl-L-cysteine to glutathione. Defects in Glutathione Synthetase can also cause the glutathione synthetase deficiency of erythrocytes, which is a mild form causing hemolytic anemia.

Product Name:Human GSS Recombinant Protein (RPES5105)
Product Code:RPES5105
Size:10µg
Species:Human
Expressed Host:E.coli
Synonyms:Glutathione Synthetase, GSH Synthetase, GSH-S, Glutathione Synthase, GSS
Accession:P48637
Sequence:Ala2-Val474
Fusion tag:C-6His
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Human Glutathione Synthetase is produced by our E.coli expression system and the target gene encoding Ala2-Val474 is expressed with a 6His tag at the C-terminus.
Purity:> 95 % as determined by reducing SDS-PAGE.
Mol Mass:53.5 kDa
AP Mol Mass:55 kDa
Formulation:Supplied as a 0.2 µm filtered solution of 20mM TrisHCl, 200mM NaCl, pH 7.5 .
Shipping:This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C.
Stability and Storage:Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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Additional Information

Product Type:
Recombinant Protein
Species:
Human
Research Area:
Metabolism
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