Enzymes Recombinant Proteins
Human GPX7 Recombinant Protein (RPPB1746)
- SKU:
- RPPB1746
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- Q96SL4
- Research Area:
- Enzymes
Description
| Product Name: | Human GPX7 Recombinant Protein |
| Product Code: | RPPB1746 |
| Size: | 20µg |
| Species: | Human |
| Target: | GPX7 |
| Synonyms: | Glutathione peroxidase 7, glutathione peroxidase 6, GPX6, NPGPx, CL683, GPx-7, GSHPx-7, non-selenocysteine containing phospholipid hydroperoxide glutathione peroxidase, FLJ14777, EC 1.11.1.9. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | The GPX7 solution (1mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 100mM NaCl, 1mM DTT and 20% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 95% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSHMQQEQD FYDFKAVNIR GKLVSLEKYR GSVSLVVNVA SECGFTDQHY RALQQLQRDL GPHHFNVLAF PCNQFGQQEP DSNKEIESFA RRTYSVSFPM FSKIAVTGTG AHPAFKYLAQ TSGKEPTWNF WKYLVAPDGK VVGAWDPTVS VEEVRPQITA LVRKLILLKR EDL |
GPX7 is a member of the glutathione peroxidase family. Glutathione peroxidases (GPx) are a family of enzymes with peroxidase activity whose central biological role is to guard the organism from oxidative damage by reducing lipid hydroperoxides to their corresponding alcohols and to reduce free hydrogen peroxide to water.
GPX7 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 193 amino acids (20-187) and having a molecular mass of 21.8kDa.GPX7 is fused to a 25 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | GPX7: Belongs to the glutathione peroxidase family. |
| UniProt Protein Details: | Protein type:Secreted; Secreted, signal peptide; Other Amino Acids Metabolism - glutathione; Oxidoreductase; EC 1.11.1.9; Lipid Metabolism - arachidonic acid Chromosomal Location of Human Ortholog: 1p32 Cellular Component: endoplasmic reticulum; endoplasmic reticulum lumen; extracellular region Molecular Function:peroxidase activity; glutathione peroxidase activity Biological Process: response to reactive oxygen species |
| UniProt Code: | Q96SL4 |
| NCBI GenInfo Identifier: | 33516901 |
| NCBI Gene ID: | 2882 |
| NCBI Accession: | Q96SL4.1 |
| UniProt Secondary Accession: | Q96SL4,O95337, Q5T501, |
| UniProt Related Accession: | Q96SL4 |
| Molecular Weight: | 187 |
| NCBI Full Name: | Glutathione peroxidase 7 |
| NCBI Synonym Full Names: | glutathione peroxidase 7 |
| NCBI Official Symbol: | GPX7�� |
| NCBI Official Synonym Symbols: | GPX6; CL683; GPx-7; NPGPx; GSHPx-7�� |
| NCBI Protein Information: | glutathione peroxidase 7; glutathione peroxidase 6; non-selenocysteine containing phospholipid hydroperoxide glutathione peroxidase |
| UniProt Protein Name: | Glutathione peroxidase 7 |
| UniProt Synonym Protein Names: | CL683 |
| Protein Family: | Glutathione peroxidase |
| UniProt Gene Name: | GPX7�� |
| UniProt Entry Name: | GPX7_HUMAN |
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