Human GPR77 Full-Length Bioactive Membrane Protein (HDFP050)

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SKU:
HDFP050
Product Type:
Recombinant Protein
Protein Type:
Full-Length Bioactive Membrane Protein
Species:
Human
Uniprot:
Q9P296

Description

system_update_altDatasheet
Product nameHuman GPR77 full length protein-synthetic nanodisc
Size:10ug
Product SKU:HDFP050
Product CategoryFull Length Transmembrane Proteins
Target:C5AR2
Uniprot:Q9P296
Description:Human GPR77 full length protein-synthetic nanodisc
Molecular Weight:The human full length C5AR2 protein has a MW of 36.1 kDa
Protein Family:Druggable Genome, GPCR, Transmembrane
Protein Pathways:
Storage & Shipping:Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Synonyms:C5L2; GPF77; GPR77
Expression System:HEK293
Formulation:Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions.
Background:This gene encodes a G-protein coupled receptor 1 family member involved in the complement system of the innate immune response. Unlike classical G-protein coupled receptors, the encoded protein does not associate with intracellular G-proteins. It may instead modulate signal transduction through the beta-arrestin pathway, and may alternatively act as a decoy receptor. This gene may be involved in coronary artery disease and in the pathogenesis of sepsis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012]
Delivery:3-4 weeks
UsageResearch use only
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