Human GPNMB Recombinant Protein (RPES2918)
- SKU:
- RPES2918
- Product Type:
- Recombinant Protein
- Species:
- Human
Description
system_update_altDatasheet
Human GPNMB Recombinant Protein
Osteoactivin is an intracellular glycoprotein belongs to the NMB/pMEL-17 family; which is asscociated with cell endosomal/lysomal compartments. Human Osteoactivin is a 560 amino acid type I transmembrane protein; and one alternate splice form shows a 12 amino acid insert between amino acid 339-340. An additional 206 amino acid isoform shows a mutation at position 181 that results in a 26 amino acid substitution for the C-terminal 380 amino acids. Cells knowns to express Osteoactivin include fibroblast; osteoblasts; myeloid dendritic cell; melanocytes; plus fetal chondrocytes and stratum basale keratinocytes; macrophages/keratinocytes.
| Product Name: | Human GPNMB Recombinant Protein (RPES2918) |
| Product Code: | RPES2918 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | Human Cells |
| Synonyms: | Transmembrane Glycoprotein NMB, Transmembrane Glycoprotein HGFIN, GPNMB, HGFIN,NMB,Osteoactivin |
| Accession: | Q14956-2 |
| Sequence: | Ala22-Pro486 |
| Fusion tag: | C-6His |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Human Glycoprotein Non-Metastatic Melanoma Protein B is produced by our Mammalian expression system and the target gene encoding Ala22-Pro486 is expressed with a 6His tag at the C-terminus. |
| Purity: | > 95 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 53.1 kDa |
| AP Mol Mass: | 100 kDa |
| Formulation: | Lyophilized from a 0.2 µm filtered solution of 20mM PB; 150mM NaCl; pH 7.2. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
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