Enzymes Recombinant Proteins

Human GOT2 Recombinant Protein (RPPB1725)

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SKU:
RPPB1725
Product Type:
Recombinant Protein
Species:
Human
Uniprot:
P00505
Research Area:
Enzymes

Description

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Product Name:Human GOT2 Recombinant Protein
Product Code:RPPB1725
Size:20µg
Species:Human
Target:GOT2
Synonyms:EC 2.6.1.1, Aspartate aminotransferase 1, Transaminase A, GIG18.
Source:Escherichia Coli
Physical Appearance:Sterile filtered colorless solution.
Formulation:The GOT2 solution (0.5mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 10% glycerol and 1mM DTT.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 95.0% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MGSSSWWTHV EMGPPDPILG VTEAFKRDTN SKKMNLGVGA YRDDNGKPYV LPSVRKAEAQ IAAKNLDKEY LPIGGLAEFC KASAELALGE NSEVLKSGRF VTVQTISGTG ALRIGASFLQ RFFKFSRDVF LPKPTWGNHT PIFRDAGMQL QGYRYYDPKT�CGFDFTGAVE DISKIPEQSV LLLHACAHNP TGVDPRPEQW KEIATVVKKR NLFAFFDMAY QGFASGDGDK DAWAVRHFIE QGINVCLCQS YAKNMGLYGE RVGAFTMVCK DADEAKRVES QLKILIRPMY SNPPLNGARI AAAILNTPDL RKQWLQEVKV MADRIIGMRT QLVSNLKKEG�STHNWQHITD QIGMFCFTGL KPEQVERLIK EFSIYMTKDG RISVAGVTSS NVGYLAHAIH QVTK

GOT2 is a pyridoxal phosphate-dependent enzyme which is found in cytoplasmic and inner-membrane mitochondrial forms, GOT1 and GOT2. GOT2 is invloved in amino acid metabolism and the urea and tricarboxylic acid cycles. The 2 enzymes are homodimeric and demonstrate close homology.

GOT2 Recombinant Human produced in E.Coli is a single, non-glycosylated polypeptide chain containing 424 amino acids (30-430 a.a.) and having a molecular mass of 47kDa. The GOT2 fused to a 23 amino acid his tag at N-terminus and is purified by proprietary chromatographic techniques.

UniProt Code:P00505
NCBI GenInfo Identifier:73486658
NCBI Gene ID:2806
NCBI Accession:NP_002071.2
UniProt Secondary Accession:P00505,Q53FL3, Q9BWA3,
UniProt Related Accession:P00505
Molecular Weight:430
NCBI Full Name:aspartate aminotransferase, mitochondrial
NCBI Synonym Full Names:glutamic-oxaloacetic transaminase 2, mitochondrial
NCBI Official Symbol:GOT2��
NCBI Official Synonym Symbols:KAT4; KATIV; mitAAT��
NCBI Protein Information:aspartate aminotransferase, mitochondrial; FABP-1; FABPpm; mAspAT; transaminase A; aspartate transaminase 2; fatty acid-binding protein; aspartate aminotransferase 2; kynurenine aminotransferase 4; kynurenine aminotransferase IV; glutamate oxaloacetate tr
UniProt Protein Name:Aspartate aminotransferase, mitochondrial
UniProt Synonym Protein Names:Fatty acid-binding protein; FABP-1; Glutamate oxaloacetate transaminase 2; Kynurenine aminotransferase 4; Kynurenine aminotransferase IV; Kynurenine--oxoglutarate transaminase 4; Kynurenine--oxoglutarate transaminase IV; Plasma membrane-associated fatty acid-binding protein; FABPpm; Transaminase A
UniProt Gene Name:GOT2��
UniProt Entry Name:AATM_HUMAN
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