Description
| Product Name: | Human GOT2 Recombinant Protein |
| Product Code: | RPPB1725 |
| Size: | 20µg |
| Species: | Human |
| Target: | GOT2 |
| Synonyms: | EC 2.6.1.1, Aspartate aminotransferase 1, Transaminase A, GIG18. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile filtered colorless solution. |
| Formulation: | The GOT2 solution (0.5mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 10% glycerol and 1mM DTT. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 95.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSSSWWTHV EMGPPDPILG VTEAFKRDTN SKKMNLGVGA YRDDNGKPYV LPSVRKAEAQ IAAKNLDKEY LPIGGLAEFC KASAELALGE NSEVLKSGRF VTVQTISGTG ALRIGASFLQ RFFKFSRDVF LPKPTWGNHT PIFRDAGMQL QGYRYYDPKT�CGFDFTGAVE DISKIPEQSV LLLHACAHNP TGVDPRPEQW KEIATVVKKR NLFAFFDMAY QGFASGDGDK DAWAVRHFIE QGINVCLCQS YAKNMGLYGE RVGAFTMVCK DADEAKRVES QLKILIRPMY SNPPLNGARI AAAILNTPDL RKQWLQEVKV MADRIIGMRT QLVSNLKKEG�STHNWQHITD QIGMFCFTGL KPEQVERLIK EFSIYMTKDG RISVAGVTSS NVGYLAHAIH QVTK |
GOT2 is a pyridoxal phosphate-dependent enzyme which is found in cytoplasmic and inner-membrane mitochondrial forms, GOT1 and GOT2. GOT2 is invloved in amino acid metabolism and the urea and tricarboxylic acid cycles. The 2 enzymes are homodimeric and demonstrate close homology.
GOT2 Recombinant Human produced in E.Coli is a single, non-glycosylated polypeptide chain containing 424 amino acids (30-430 a.a.) and having a molecular mass of 47kDa. The GOT2 fused to a 23 amino acid his tag at N-terminus and is purified by proprietary chromatographic techniques.
| UniProt Code: | P00505 |
| NCBI GenInfo Identifier: | 73486658 |
| NCBI Gene ID: | 2806 |
| NCBI Accession: | NP_002071.2 |
| UniProt Secondary Accession: | P00505,Q53FL3, Q9BWA3, |
| UniProt Related Accession: | P00505 |
| Molecular Weight: | 430 |
| NCBI Full Name: | aspartate aminotransferase, mitochondrial |
| NCBI Synonym Full Names: | glutamic-oxaloacetic transaminase 2, mitochondrial |
| NCBI Official Symbol: | GOT2�� |
| NCBI Official Synonym Symbols: | KAT4; KATIV; mitAAT�� |
| NCBI Protein Information: | aspartate aminotransferase, mitochondrial; FABP-1; FABPpm; mAspAT; transaminase A; aspartate transaminase 2; fatty acid-binding protein; aspartate aminotransferase 2; kynurenine aminotransferase 4; kynurenine aminotransferase IV; glutamate oxaloacetate tr |
| UniProt Protein Name: | Aspartate aminotransferase, mitochondrial |
| UniProt Synonym Protein Names: | Fatty acid-binding protein; FABP-1; Glutamate oxaloacetate transaminase 2; Kynurenine aminotransferase 4; Kynurenine aminotransferase IV; Kynurenine--oxoglutarate transaminase 4; Kynurenine--oxoglutarate transaminase IV; Plasma membrane-associated fatty acid-binding protein; FABPpm; Transaminase A |
| UniProt Gene Name: | GOT2�� |
| UniProt Entry Name: | AATM_HUMAN |
