Human GNGT1 Recombinant Protein (RPPB3624)
- SKU:
- RPPB3624
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- P63211
Description
| Product Name: | Human GNGT1 Recombinant Protein |
| Product Code: | RPPB3624 |
| Size: | 20µg |
| Species: | Human |
| Target: | GNGT1 |
| Synonyms: | GuanineNucleotide Binding Protein (G Protein), Gamma Transducing Activity Polypeptide1, Transducin Gamma Chain, Guanine Nucleotide-Binding Protein G(T) SubunitGamma-T1, GNG1, Guanine nucleotide-binding protein G(T) subunit gamma-T1. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | GNGT1 protein solution (1mg/ml) containing 20mM Tris-HClbuffer (pH8.0), 10% glycerol, 0.1M NaCl and 1mM EDTA. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 95.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHHSSGLVPRGSH MGSMPVINIEDLTEKDKLKM EVDQLKKEVT LERMLVSKCC EEVRDYVEER SGEDPLVKGI PEDKNPFKEL KGGC |
Guanine Nucleotide Binding Protein Gamma Transducing 1, also known asGNGT1 is amember of the G protein gamma family. GNGT1 is implicated in varioustransmembrane signaling systems as a modulator or transducer.� In addition GNGT1 (beta & gamma chains)is required for the GTPase activity, for replacement of GDP by GTP, and for Gprotein- effector interaction.
GNGT1 Human Recombinant produced in E.Coli is a single,non-glycosylated polypeptide chain containing 94 amino acids (1-71 a.a) andhaving a molecular mass of 10.6kDa.GNGT1 is fused to a 23 amino acid His-tag at N-terminus& purified by proprietary chromatographic techniques.
| UniProt Protein Function: | G-gamma t1: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction. Belongs to the G protein gamma family. |
| UniProt Protein Details: | Protein type:G protein; G protein, heterotrimeric gamma; G protein, heterotrimeric Chromosomal Location of Human Ortholog: 7q21.3 Cellular Component: plasma membrane Molecular Function:GTPase activity; protein binding Biological Process: regulation of rhodopsin mediated signaling; rhodopsin mediated signaling |
| NCBI Summary: | This gene encodes the gamma subunit of transducin, a guanine nucleotide-binding protein (G protein) that is found in rod outer segments. Transducin, also known as GMPase, mediates the activation of a cyclic GTP-specific (guanosine monophosphate) phosphodiesterase by rhodopsin. [provided by RefSeq, Jul 2016] |
| UniProt Code: | P63211 |
| NCBI GenInfo Identifier: | 52783592 |
| NCBI Gene ID: | 2792 |
| NCBI Accession: | P63211.2 |
| UniProt Secondary Accession: | P63211,O43835, Q08447, Q16026, Q6LCP6, A4D1H2, |
| UniProt Related Accession: | P63211 |
| Molecular Weight: | 8,496 Da |
| NCBI Full Name: | Guanine nucleotide-binding protein G(T) subunit gamma-T1 |
| NCBI Synonym Full Names: | G protein subunit gamma transducin 1 |
| NCBI Official Symbol: | GNGT1�� |
| NCBI Official Synonym Symbols: | GNG1�� |
| NCBI Protein Information: | guanine nucleotide-binding protein G(T) subunit gamma-T1 |
| UniProt Protein Name: | Guanine nucleotide-binding protein G(T) subunit gamma-T1 |
| UniProt Synonym Protein Names: | Transducin gamma chain |
| UniProt Gene Name: | GNGT1�� |
| UniProt Entry Name: | GBG1_HUMAN |
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