Human GNG12 Recombinant Protein (RPPB3622)

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SKU:
RPPB3622
Product Type:
Recombinant Protein
Species:
Human
Uniprot:
Q9UBI6

Description

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Product Name:Human GNG12 Recombinant Protein
Product Code:RPPB3622
Size:20µg
Species:Human
Target:GNG12
Synonyms:Guanine Nucleotide Binding Protein (G Protein), Gamma 12,Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered colorless solution.
Formulation:GNG12protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH 8.0) and 10%glycerol.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 85.0% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MGSMSSKTAS TNNIAQARRT VQQLRLEASI ERIKVSKASA DLMSYCEEHARSDPLLIGIP TSENPFKDKK TC

Guanine Nucleotide Binding Protein Gamma 12, also known as GNG12 belongsto the Guanine nucleotide-binding proteins (G proteins) which are involved as amodulator or transducer in a variety of transmembrane signaling systems. Inaddition, the beta as well as gamma chains are essential for the GTPaseactivity, for replacement of GDP by GTP, and also for G protein-effector interaction.

GNG12 Human Recombinant produced in E.Coli is a single, non-glycosylatedpolypeptide chain containing 92 amino acids (1-69 a.a) and having a molecularmass of 10.1kDa.GNG12 is fused to a 23 amino acid His-tag at N-terminus& purified by proprietary chromatographic techniques.

UniProt Protein Function:G-gamma 12: a guanine nucleotide-binding protein of the G protein gamma family. Heterotrimeric G proteins are composed of 3 units; alpha, beta and gamma. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. Protein type: G protein, heterotrimeric gamma; G protein; G protein, heterotrimericChromosomal Location of Human Ortholog: 1p31.3Cellular Component: plasma membraneMolecular Function: PDZ domain binding; protein bindingBiological Process: signal transduction
UniProt Protein Details:
NCBI Summary:
UniProt Code:Q9UBI6
NCBI GenInfo Identifier:12229817
NCBI Gene ID:55970
NCBI Accession:Q9UBI6.3
UniProt Secondary Accession:Q9UBI6,Q69YP5, Q9BRV5
UniProt Related Accession:Q9UBI6
Molecular Weight:8,006 Da
NCBI Full Name:Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
NCBI Synonym Full Names:G protein subunit gamma 12
NCBI Official Symbol:GNG12��
NCBI Official Synonym Symbols:
NCBI Protein Information:guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
UniProt Protein Name:Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
UniProt Synonym Protein Names:
Protein Family:
UniProt Gene Name:GNG12��
UniProt Entry Name:GBG12_HUMAN
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