Human GNG12 Recombinant Protein (RPPB3622)
- SKU:
- RPPB3622
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- Q9UBI6
Description
| Product Name: | Human GNG12 Recombinant Protein |
| Product Code: | RPPB3622 |
| Size: | 20µg |
| Species: | Human |
| Target: | GNG12 |
| Synonyms: | Guanine Nucleotide Binding Protein (G Protein), Gamma 12,Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | GNG12protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH 8.0) and 10%glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 85.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSMSSKTAS TNNIAQARRT VQQLRLEASI ERIKVSKASA DLMSYCEEHARSDPLLIGIP TSENPFKDKK TC |
Guanine Nucleotide Binding Protein Gamma 12, also known as GNG12 belongsto the Guanine nucleotide-binding proteins (G proteins) which are involved as amodulator or transducer in a variety of transmembrane signaling systems. Inaddition, the beta as well as gamma chains are essential for the GTPaseactivity, for replacement of GDP by GTP, and also for G protein-effector interaction.
GNG12 Human Recombinant produced in E.Coli is a single, non-glycosylatedpolypeptide chain containing 92 amino acids (1-69 a.a) and having a molecularmass of 10.1kDa.GNG12 is fused to a 23 amino acid His-tag at N-terminus& purified by proprietary chromatographic techniques.
| UniProt Protein Function: | G-gamma 12: a guanine nucleotide-binding protein of the G protein gamma family. Heterotrimeric G proteins are composed of 3 units; alpha, beta and gamma. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. Protein type: G protein, heterotrimeric gamma; G protein; G protein, heterotrimericChromosomal Location of Human Ortholog: 1p31.3Cellular Component: plasma membraneMolecular Function: PDZ domain binding; protein bindingBiological Process: signal transduction |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q9UBI6 |
| NCBI GenInfo Identifier: | 12229817 |
| NCBI Gene ID: | 55970 |
| NCBI Accession: | Q9UBI6.3 |
| UniProt Secondary Accession: | Q9UBI6,Q69YP5, Q9BRV5 |
| UniProt Related Accession: | Q9UBI6 |
| Molecular Weight: | 8,006 Da |
| NCBI Full Name: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 |
| NCBI Synonym Full Names: | G protein subunit gamma 12 |
| NCBI Official Symbol: | GNG12�� |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 |
| UniProt Protein Name: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 |
| UniProt Synonym Protein Names: | |
| Protein Family: | |
| UniProt Gene Name: | GNG12�� |
| UniProt Entry Name: | GBG12_HUMAN |
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