Human GNG11 Recombinant Protein (RPPB3621)

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RPPB3621

Description

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Product Name:Human GNG11 Recombinant Protein
Product Code:RPPB3621
Size:20µg
Species:Human
Target:GNG11
Synonyms:GNGT11, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11, GNG11.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered clear solution.
Formulation:The GNG11 solution (1mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 10% glycerol and 1mM DTT.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 90% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MGSMPALHIE DLPEKEKLKM EVEQLRKEVK LQRQQVSKCS EEIKNYIEER SGEDPLVKGI PEDKNPFKEK GSC

Guanine Nucleotide Binding Protein Gamma 11 (GNG11) which belongs to the guanine nucleotide-binding protein (G protein) gamma family encodes a lipid-anchored, cell membrane protein. G proteins act as a modulator or transducer in various transmembrane signaling systems. GNG11 is also subject to carboxyl-terminal processing.

GNG11 Human Recombinant produced in E. coli is. a single polypeptide chain containing 93 amino acids (1-70) and having a molecular mass of 10.6kDa. GNG11 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

UniProt Protein Function:G-gamma 11: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction. Belongs to the G protein gamma family.Protein type: G protein, heterotrimeric gammaChromosomal Location of Human Ortholog: 7q21Cellular Component: heterotrimeric G-protein complex; plasma membraneMolecular Function: GTPase activity; signal transducer activityBiological Process: energy reserve metabolic process; G-protein coupled receptor protein signaling pathway; signal transduction
UniProt Protein Details:
NCBI Summary:This gene is a member of the guanine nucleotide-binding protein (G protein) gamma family and encodes a lipid-anchored, cell membrane protein. As a member of the heterotrimeric G protein complex, this protein plays a role in this transmembrane signaling system. This protein is also subject to carboxyl-terminal processing. Decreased expression of this gene is associated with splenic marginal zone lymphomas. [provided by RefSeq, Jul 2008]
UniProt Code:P61952
NCBI GenInfo Identifier:4758448
NCBI Gene ID:2791
NCBI Accession:NP_004117.1
UniProt Secondary Accession:P61952,P50152
UniProt Related Accession:P61952
Molecular Weight:8,481 Da
NCBI Full Name:guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
NCBI Synonym Full Names:guanine nucleotide binding protein (G protein), gamma 11
NCBI Official Symbol:GNG11��
NCBI Official Synonym Symbols:GNGT11��
NCBI Protein Information:guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
UniProt Protein Name:Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
UniProt Synonym Protein Names:
Protein Family:
UniProt Gene Name:GNG11��
UniProt Entry Name:GBG11_HUMAN
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Additional Information

Product Type:
Recombinant Protein
Species:
Human
Uniprot:
P61952
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