Metabolism Recombinant Proteins

Human GMPR Recombinant Protein (RPES3792)

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SKU:
RPES3792
Product Type:
Recombinant Protein
Species:
Human
Research Area:
Metabolism

Description

system_update_altDatasheet

Human GMPR Recombinant Protein

GMPR; also known as GMPR1; belongs to the IMPDH/GMPR family. This family of enzymes includes IMP dehydrogenase and GMP reductase. These enzymes are involved in purine metabolism and adopt a TIM barrel structure. GMPR is an enzyme that catalyzes the irreversible and NADPH-dependent reductive deamination of GMP to IMP. GMPR functions in the conversion of nucleobase; nucleoside and nucleotide derivatives of G to A nucleotides; and in maintaining the intracellular balance of A and G nucleotides.

Product Name:Human GMPR Recombinant Protein (RPES3792)
Product Code:RPES3792
Size:20µg
Species:Human
Expressed Host:E.coli
Synonyms:GMP Reductase 1, Guanosine 5'-Monophosphate Oxidoreductase 1, Guanosine Monophosphate Reductase 1, GMPR, GMPR1
Accession:P36959
Sequence:Met 1-Ser345
Fusion tag:N-His
Endotoxin:Please contact us for more information.
Protein Construction:A DNA sequence encoding the human GMPR (Met1-Ser345) was expressed with a polyhistidine tag at the N-terminus.
Purity:> 85 % as determined by reducing SDS-PAGE.
Mol Mass:39.2 kDa
AP Mol Mass:37 kDa
Formulation:Lyophilized from sterile 50mM Tris; 150mM NaCl; 40% Glycerol; 1mM DTT; pH 8.0
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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Metabolism Recombinant Proteins

system_update_altDatasheetHuman GMPR Recombinant Protein GMP Reductase 1 (GMPR) is a member of the IMPDH/GMPR family. GMPR exists as a homotetramer and catalyzes the irreversible NADPH-dependent