Human GLP1R Recombinant Protein (RPES2530)
- SKU:
- RPES2530
- Product Type:
- Recombinant Protein
- Species:
- Human
Description
Human GLP1R Recombinant Protein
GLP1R is a 7-transmembrane protein that functions as a receptor for the glucagon-like peptide 1 (GLP-1) hormone. GLP-1 stimulates glucose-induced insulin secretion. This receptor, which is found on the cell surface and plays a role in insulin release signalling pathways in response to GLP-1 and GLP-1 analogues, is internalised. In animal studies, GLP1R has been linked to brain health due to it's function in neuroprotective. For type 2 diabetes and stroke treatment, the protein is a promising therapeutic target. Polymorphisms in the GLP1R gene are linked to diabetes, indicating that the protein is a promising drug target for type 2 diabetes treatment. Hyperglycemia and insulinoma are two diseases linked to the GLP1R. GLP1R has been linked with the presynaptic function and G alpha (s) signalling events of Kainate receptors. Human GLP1R Recombinant Protein is a highly pure recombinant protein developed by Assay Genie for use in a range of applications.
| Product Name: | Human GLP1R Recombinant Protein (RPES2530) |
| Product Code: | RPES2530 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | Human Cells |
| Synonyms: | Glucagon-like peptide 1 receptor, GLP-1 receptor, GLP-1-R |
| Accession: | P43220 |
| Sequence: | Arg24-Tyr145 |
| Fusion tag: | C-Fc |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Human LP1R is produced by our Mammalian expression system and the target gene encoding Arg24-Tyr145 is expressed with a Fc tag at the C-terminus. |
| Purity: | > 90% as determined by reducing SDS-PAGE. |
| Mol Mass: | 41.2 kDa |
| AP Mol Mass: | 55-60 kDa |
| Formulation: | Lyophilized from a 0.2 µm filtered solution of PBS, pH7.4. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
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