Human GLOD4 Recombinant Protein (RPPB3606)
- SKU:
- RPPB3606
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- Q9HC38
Description
| Product Name: | Human GLOD4 Recombinant Protein |
| Product Code: | RPPB3606 |
| Size: | 20µg |
| Species: | Human |
| Target: | GLOD4 |
| Synonyms: | Glyoxalase domain containing protein 4, HC71, C17orf25, CGI-150, Chromosome 17 open reading frame 25. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | The GLOD4 solution (1mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 1mM DTT, 0.1M NaCl and 20% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 95% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MAARRALHFV FKVGNRFQTA RFYRDVLGMK VLRHEEFEEG CKAACNGPYD GKWSKTMVGF GPEDDHFVAE LTYNYGVGDY KLGNDFMGIT LASSQAVSNA RKLEWPLTEV AEGVFETEAP GGYKFYLQNR SLPQSDPVLK VTLAVSDLQK SLNYWCNLLG MKIYEKDEEK QRALLGYADN QCKLELQGVK GGVDHAAAFG RIAFSCPQKE LPDLEDLMKR ENQKILTPLV SLDTPGKATV QVVILADPDG HEICFVGDEA FRELSKMDPE GSKLLDDAMA ADKSDEWFAK HNKPKASG |
GLOD4 is a part of the glyoxalase system which is a group of enzymes that is in charge of the detoxification of methylglyoxal and other reactive aldehydes that are usually produced in metabolism. The mitochondrial protein GLOD4 is known to interact with NUDT9.
GLOD4 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 318 amino acids (1-298) and having a molecular mass of 35.3 kDa.The GLOD4 is fused to a 20 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques.
| UniProt Protein Function: | GLOD4: Belongs to the glyoxalase I family. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Mitochondrial Chromosomal Location of Human Ortholog: 17p13.3 Cellular Component: mitochondrion |
| UniProt Code: | Q9HC38 |
| NCBI GenInfo Identifier: | 74718831 |
| NCBI Gene ID: | 51031 |
| NCBI Accession: | Q9HC38.1 |
| UniProt Secondary Accession: | Q9HC38,Q96B89, Q9H3J8, Q9HC37, Q9NVN1, D3DTG9, D3DTH1 |
| UniProt Related Accession: | Q9HC38 |
| Molecular Weight: | 21,258 Da |
| NCBI Full Name: | Glyoxalase domain-containing protein 4 |
| NCBI Synonym Full Names: | glyoxalase domain containing 4 |
| NCBI Official Symbol: | GLOD4�� |
| NCBI Official Synonym Symbols: | HC71; CGI-150; C17orf25�� |
| NCBI Protein Information: | glyoxalase domain-containing protein 4 |
| UniProt Protein Name: | Glyoxalase domain-containing protein 4 |
| Protein Family: | Glyoxalase domain-containing protein |
| UniProt Gene Name: | GLOD4�� |
| UniProt Entry Name: | GLOD4_HUMAN |
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