Immune Checkpoint Recombinant Proteins
Human GITR Recombinant Protein (mFc-His Tag) (HDPT0019)
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- SKU:
- HDPT0019
- Product Type:
- Recombinant Protein
- Species:
- Human
- Research Area:
- Immune Checkpoint
Description
Human GITR Recombinant Protein (mFc-His Tag)
| Description: | This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. |
| Product name: | Human GITR Recombinant Protein (mFc-His Tag) |
| Synonyms: | AITR, GITR, TNFRSF18, CD357 |
| Type: | protein |
| Size: | 50 µg |
| Name: | GITR |
| Origin: | Human |
| Source: | HEK293 |
| Protein Type: | Recombinant |
| Application: | Flow Cyt |
| Purity: | > 95% |
| Purification: | affinity purification |
| Format: | Lyophilized |
| Conjugate: | C-Mouse Fc and 6×His tag |
| Storage: | Store at -80°C for 12 months (Avoid repeated freezing and thawing) |
| Usage: | Research use only |
| Buffer: | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization. |
| Reconstitution: | Reconstitute with deionized water |
| Sequence: | GITR（Gln26-Pro162）+mFc（Pro99-Lys330）+6×His |
| Gene ID: | 8784 |
| Uniprot: | Q9Y5U5 |
| Molecular Weight: | 50-52 kDa |
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