Immune Checkpoint Recombinant Proteins

Human GITR Recombinant Protein (hFc-His Tag) (HDPT0018)

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SKU:
HDPT0018
Product Type:
Recombinant Protein
Species:
Human
Research Area:
Immune Checkpoint

Description

Human GITR Recombinant Protein (hFc-His Tag)

Description:This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Product name:Human GITR Recombinant Protein (hFc-His Tag)
Synonyms:AITR, GITR, TNFRSF18, CD357
Type:protein
Size:50 µg
Name:GITR
Origin:Human
Source:HEK293
Protein Type:Recombinant
Application:Contact Technical Support
Purity:> 95%
Purification:affinity purification
Format:Lyophilized
Conjugate:C-Human Fc and 6×His tag
Storage:Store at -80°C for 12 months (Avoid repeated freezing and thawing)
Usage:Research use only
Buffer:Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
Reconstitution:Reconstitute with deionized water
Sequence:GITR(Gln26-Pro162)+hFc(Glu99-Ala330)+6×His
Gene ID:8784
Uniprot:Q9Y5U5
Molecular Weight:51-52 kDa
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