Human GIPR Full-Length Bioactive Membrane Protein (HDFP111)

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SKU:
HDFP111

Description

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Product nameHuman GIPR full length protein-synthetic nanodisc
Size:10ug
Product SKU:HDFP111
Product CategoryFull Length Transmembrane Proteins
Target:GIPR
Uniprot:P48546
Description:Human GIPR full length protein-synthetic nanodisc
Molecular Weight:The human full length GIPR protein has a MW of 53 kDa
Protein Family:Druggable Genome, GPCR, Transmembrane
Protein Pathways:Neuroactive ligand-receptor interaction
Storage & Shipping:Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Synonyms:PGQTL2
Expression System:HEK293
Formulation:Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions.
Background:This gene encodes a G-protein coupled receptor for gastric inhibitory polypeptide (GIP), which was originally identified as an activity in gut extracts that inhibited gastric acid secretion and gastrin release, but subsequently was demonstrated to stimulate insulin release in the presence of elevated glucose. Mice lacking this gene exhibit higher blood glucose levels with impaired initial insulin response after oral glucose load. Defect in this gene thus may contribute to the pathogenesis of diabetes. [provided by RefSeq, Oct 2011]
Delivery:3-4 weeks
UsageResearch use only
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Additional Information

Product Type:
Recombinant Protein
Protein Type:
Full-Length Bioactive Membrane Protein
Species:
Human
Uniprot:
P48546
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