Human GDF-5 / BMP14 ELISA Kit

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SKU:
HUFI00719
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
P43026
Sensitivity:
0.094ng/ml
Range:
0.156-10ng/ml
ELISA Type:
Sandwich
Synonyms:
GDF5, BMP-14, CDMP-1, BMP14, Cartilage-derived morphogenetic protein 1, cartilage-derived morphogenetic protein-1, CDMP1LAP4, GDF-5, growth differentiation factor 5, growth, differentiation factor 5, OS5, Radotermin, radotermin, SYNS2
Reactivity:
Human
Research Area:
Cell Biology

Description

Human GDF-5 / BMP14 ELISA

GDF-5 / BMP14 binds various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. GDF-5 / BMP14 regulates the development of numerous tissue and cell types, including cartilage, joints, brown fat, teeth, and the growth of neuronal axons and dendrites. Mutations in the GDF-5 / BMP14 gene are associated with acromesomelic dysplasia, brachydactyly, chondrodysplasia, and susceptibility to osteoarthritis.

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