Human GCDH Recombinant Protein (RPES5067)

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SKU:
RPES5067
Product Type:
Recombinant Protein
Species:
Human

Description

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Human GCDH Recombinant Protein

Glutaryl-CoA Dehydrogenase Mitochondrial (GCDH) is an enzyme that acts upon glutaryl-coenzyme A, creating crotonyl-coenzyme A. It plays a role in the metabolism of lysine, hydroxylysine and tryptophan. It uses electron transfer flavoprotein as its electron acceptor. Isoform Short is inactive Glutaryl-CoA and electron-transfer flavoprotein to (E)-but-2-enoyl-CoA, CO2 and reduced electron-transfer flavoprotein. A defect in this enzyme is associated with neurological condition glutaric acidemia type 1 and cause a progressive form of early-onset generalized dystonia.

Product Name:Human GCDH Recombinant Protein (RPES5067)
Product Code:RPES5067
Size:10µg
Species:Human
Expressed Host:E.coli
Synonyms:Glutaryl-CoA Dehydrogenase Mitochondrial, GCD, GCDH
Accession:Q92947
Sequence:Arg45-Lys438
Fusion tag:N-6His
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Human Glutaryl-CoA Dehydrogenase, Mitochondrial is produced by our E.coli expression system and the target gene encoding Arg45-Lys438 is expressed with a 6His tag at the N-terminus.
Purity:> 95 % as determined by reducing SDS-PAGE.
Mol Mass:45.0 kDa
AP Mol Mass:41 kDa
Formulation:Supplied as a 0.2 µm filtered solution of 20mM HEPES, 150mM NaCl, pH 7.4.
Shipping:This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C.
Stability and Storage:Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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