Human GARS / Glycyl tRNA Synthetase GARS protein ELISA Kit

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SKU:
HUFI02487
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
P41250
Sensitivity:
0.188ng/ml
Range:
0.313-20ng/ml
ELISA Type:
Sandwich
Synonyms:
GARS, GlyRS, AP-4-A synthetase, Diadenosine tetraphosphate synthetase, Glycine--tRNA ligase
Reactivity:
Human
Research Area:
Metabolism

Description

Human GARS / Glycyl tRNA Synthetase GARS protein ELISA

GARS1 (Glycyl-TRNA Synthetase 1) is a mitochondrial enzyme that catalyzes the transfer of an amino group from glutamine to ribose-5-phosphate to produce glutamate and 5-phosphoribosylamine. GARS1 is required for the de novo synthesis of glutamate, which is a precursor for neurotransmitters including GABA and glutamate. GARS1 deficiency has been implicated in a wide range of neurological disorders, including epilepsy, cerebral palsy, and autism. An important paralog of GARS1 is POLG2.

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