Human GARNL3 (GTPase-activating Rap/Ran-GAP domain-like protein 3) ELISA Kit (HUFI05184)

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SKU:
HUFI05184
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
Q5VVW2
Sensitivity:
0.094ng/ml
Range:
0.156-10ng/ml
ELISA Type:
Sandwich
Synonyms:
GTPase-activating Rap, Ran-GAP domain-like protein 3
Reactivity:
Human

Description

Human GARNL3 (GTPase-activating Rap/Ran-GAP domain-like protein 3) ELISA

GARNL3 (GTPase-activating Rap/Ran-GAP domain-like protein 3) is a multifunctional protein with activity as both an inhibitor of Rap1 and activator of Ran-GAP, analogous to the Rap/Ran regulatory protein (RanBP) family. Most importantly, GARNL3 is upregulated in many cancers and has oncogenic properties that may contribute to cancer cell proliferation. GARNL3 also has a role in cell adhesion and migration. GARNL3 is associated with diseases such as cervical cancer, breast cancer, bladder cancer, acute myeloid leukemia, hepatocellular carcinoma and ovarian epithelial tumors.

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