Gankyrin is a multicatalytic proteinase oncoprotein consists of 7 ankyrin repeats. Gankyrin is over-expressed in the majority of hepatocellular carcinomas. Gankyrin is involved in the regulation of retinoblastoma protein phosphorylation by CDK4 to enhance p53 ubiquitinylation by MDM2. Gankyrin is a protein that has been linked to the development of esophageal squamous cell carcinoma. Gankyrin has been shown to play an oncogenic function, particularly in the early phases of human epatocarcinogenesis. Human Gankyrin/PSDM10 Recombinant Protein is a highly pure recombinant protein developed by Assay Genie for use in a range of applications.
Product Name:
Human Gankyrin/PSDM10 Recombinant Protein (RPES4761)