Enzymes Recombinant Proteins
Human GALM Recombinant Protein (RPPB1668)
- SKU:
- RPPB1668
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- Q96C23
- Research Area:
- Enzymes
Description
| Product Name: | Human GALM Recombinant Protein |
| Product Code: | RPPB1668 |
| Size: | 20µg |
| Species: | Human |
| Target: | GALM |
| Synonyms: | Aldose 1-epimerase, BLOCK25, IBD1, EC=5.1.3.3, GALM, galactose mutarotase. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile filtered colorless solution. |
| Formulation: | GALM solution (1mg/ml) contains 20mM Tris-HCl (pH 8.0) and 10% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.�For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 95.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MASVTRAVFG ELPSGGGTVE KFQLQSDLLR VDIISWGCTI TALEVKDRQG RASDVVLGFA ELEGYLQKQP YFGAVIGRVA NRIAKGTFKV DGKEYHLAIN KEPNSLHGGV RGFDKVLWTP RVLSNGVQFS RISPDGEEGY PGELKVWVTY TLDGGELIVN YRAQASQATP VNLTNHSYFN LAGQASPNIN DHEVTIEADT YLPVDETLIP TGEVAPVQGT AFDLRKPVEL GKHLQDFHLN GFDHNFCLKG SKEKHFCARV HHAASGRVLE VYTTQPGVQF YTGNFLDGTL KGKNGAVYPK HSGFCLETQN WPDAVNQPRF PPVLLRPGEE YDHTTWFKFS VA |
GALM is a main enzyme of carbohydrate metabolism catalysing the translation of beta-D-galactose to alpha-D-galactose. GALM is needed for normal galactose metabolism by preserveing the equilibrium of alpha and beta anomers of galactose. GALM is required for the production of complex oligosaccharides.
GALM Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 362 amino acids (1-342 a.a.) and having a molecular mass of 39.9 kDa. The GALM is fused to a 20 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques.�
| UniProt Protein Function: | GALM: Mutarotase converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose. Belongs to the aldose epimerase family. |
| UniProt Protein Details: | Protein type:EC 5.1.3.3; Carbohydrate Metabolism - glycolysis and gluconeogenesis; Isomerase Chromosomal Location of Human Ortholog: 2p22.1 Cellular Component: cytoplasm Molecular Function:aldose 1-epimerase activity; carbohydrate binding Biological Process: galactose metabolic process; glucose metabolic process |
| NCBI Summary: | This gene encodes an enzyme that catalyzes the epimerization of hexose sugars such as glucose and galactose. The encoded protein is expressed in the cytoplasm and has a preference for galactose. The encoded protein may be required for normal galactose metabolism by maintaining the equilibrium of alpha and beta anomers of galactose.[provided by RefSeq, Mar 2009] |
| UniProt Code: | Q96C23 |
| NCBI GenInfo Identifier: | 20270355 |
| NCBI Gene ID: | 130589 |
| NCBI Accession: | NP_620156 |
| UniProt Related Accession: | Q96C23 |
| Molecular Weight: | 38kDa |
| NCBI Full Name: | aldose 1-epimerase |
| NCBI Synonym Full Names: | galactose mutarotase |
| NCBI Official Symbol: | GALM�� |
| NCBI Official Synonym Symbols: | GLAT; IBD1; BLOCK25; HEL-S-63p�� |
| NCBI Protein Information: | aldose 1-epimerase |
| UniProt Protein Name: | Aldose 1-epimerase |
| UniProt Synonym Protein Names: | Galactose mutarotase |
| Protein Family: | Aldose 1-epimerase |
| UniProt Gene Name: | GALM�� |
| UniProt Entry Name: | GALM_HUMAN |
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