Human GAGE2D Recombinant Protein (RPPB3576)

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SKU:
RPPB3576
Product Type:
Recombinant Protein
Species:
Human
Uniprot:
Q9UEU5

Description

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Product Name:Human GAGE2D Recombinant Protein
Product Code:RPPB3576
Size:10µg
Species:Human
Target:GAGE2D
Synonyms:G Antigen 2D, Cancer/Testis Antigen 4.8, CT4.8, GAGE-8, GAGE8,G Antigen 8.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered clear solution.
Formulation:GAGE2D protein solution (1mg/ml) containing 20mM Tris-HClbuffer (pH8.0), 10% glycerol and 0.1M NaCl.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 95.0% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MGSMSWRGRS TYRPRPRRYV EPPEMIGPMR PEQFSDEVEP ATPEEGEPATQRQDPAAAQE GEDEGASAGQ GPKPEADSQE QGHPQTGCEC EDGPDGQEMD PPNPEEVKTP EEGEKQSQC
UniProt Code:Q9UEU5

GAGE2D is a member of the GAGE family, which organized in clusteredrepeats. In addition, they have a high degree of predicted sequence identity, butdiffer by scattered single nucleotide substitution. The first GAGE nomenclature was based onidentified mRNA sequences; however the high identity of the GAGE members made it impossible toseparate products of paralogous genes from polymorph products. Moreover GAGE2Dis not expressed in normal tissues, except in testis; however it is expressedby a large proportion of tumors of various histological origins.

GAGE2D Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 139 amino acids (1-116 a.a) and having a molecular mass of 15.2kDa (Molecular size on SDS-PAGE will appear higher).GAGE2D is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

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