Human GAGE12F Recombinant Protein (RPPB3577)

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SKU:
RPPB3577
Product Type:
Recombinant Protein
Species:
Human
Uniprot:
P0CL80

Description

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Product Name:Human GAGE12F Recombinant Protein
Product Code:RPPB3577
Size:10µg
Species:Human
Target:GAGE12F
Synonyms:G Antigen 12F, GAGE-12F, G Antigen 12F/G/I.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered clear solution.
Formulation:GAGE12F protein solution (0.25mg/ml) containing 20mMTris-HCl buffer (pH 8.0), 0.15M NaCl and 10% glycerol.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 85.0% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MGSMSWRGRS TYYWPRPRRY VQPPEMIGPM RPEQFSDEVE PATPEEGEPATQRQDPAAAQ EGEDEGASAG QGPKPEAHSQ EQGHPQTGCE CEDGPDGQEM DPPNPEEVKT PEEGEKQSQC
UniProt Code:P0CL80

GAGE12Fis a member of the GAGE multigene family expressed in a large range of tumorswhereas in normal tissues, his expression is restricted to germ cells. Thesegenes are organized in clustered repeats, and have a high degree of forecasted sequenceidentity, however differ by scattered single nucleotide substitution. Theirsequences contain either the antigenic peptide YYWPRPRRY or YRPRPRRY which isrecognized by cytotoxic T-cells.

GAGE12F Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 140 amino acids (1-117aa) and having a molecular mass of 15.4kDa.GAGE12F is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

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