Cell Cycle Recombinant Proteins

Human GADD45A/DDIT Recombinant Protein (RPES2363)

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SKU:
RPES2363
Product Type:
Recombinant Protein
Species:
Human
Research Area:
Cell Cycle

Description

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Human GADD45A/DDIT Recombinant Protein

Growth Arrest and DNA Damage-Inducible Protein GADD45 ? (GADD45A) is a member of the GADD45 family. GADD45A can be induced by UV irradiation; X-rays; growth arrest and alkylating agents; of which can be mediated by some kinases other than PKC. GADD45A can interact with MAPK14; GADD45GIP1; PCNA. In T-cells; GADD45A functions as a regulator of p38 MAPKs by inhibiting p88 phosphorylation and activity. GADD45A may affect PCNA interaction with some cell division protein kinase complexes; stimulating DNA excision repair in vitro and inhibits entry of cells into S phase.

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