Immune Checkpoint Recombinant Proteins

Human FOLR2 Recombinant Protein (hFc Tag) (HDPT0268)

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SKU:
HDPT0268
Product Type:
Recombinant Protein
Species:
Human
Research Area:
Immune Checkpoint

Description

Human FOLR2 Recombinant Protein (hFc Tag)

Description:The protein encoded by this gene is a member of the folate receptor (FOLR) family, and these genes exist in a cluster on chromosome 11. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives, and they mediate delivery of 5-methyltetrahydrofolate to the interior of cells. This protein has a 68% and 79% sequence homology with the FOLR1 and FOLR3 proteins, respectively. Although this protein was originally thought to be specific to placenta, it can also exist in other tissues, and it may play a role in the transport of methotrexate in synovial macrophages in rheumatoid arthritis patients. Multiple transcript variants that encode the same protein have been found for this gene.
Product name:Human FOLR2 Recombinant Protein (hFc Tag)
Synonyms:BETA-HFR; FBP; FBP/PL-1; FR-BETA; FR-P3; FRbeta
Type:protein
Size:50 µg
Name:FOLR2
Origin:Human
Source:HEK293
Protein Type:Recombinant
Application:Contact Technical Support
Purity:Contact Technical Support
Purification:affinity purification
Format:Lyophilized
Conjugate:C-Human Fc
Storage:Store at -80°C for 12 months (Avoid repeated freezing and thawing)
Usage:Research use only
Buffer:Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
Reconstitution:Reconstitute with deionized water
Sequence:FOLR2(Thr17-His228 )+hFc(Glu99-Ala330)
Gene ID:
Uniprot:P14207
Molecular Weight:48.84 kDa
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