Immune Checkpoint Recombinant Proteins
Human FOLR2 Recombinant Protein (hFc Tag) (HDPT0268)
- SKU:
- HDPT0268
- Product Type:
- Recombinant Protein
- Species:
- Human
- Research Area:
- Immune Checkpoint
Description
Human FOLR2 Recombinant Protein (hFc Tag)
Description: | The protein encoded by this gene is a member of the folate receptor (FOLR) family, and these genes exist in a cluster on chromosome 11. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives, and they mediate delivery of 5-methyltetrahydrofolate to the interior of cells. This protein has a 68% and 79% sequence homology with the FOLR1 and FOLR3 proteins, respectively. Although this protein was originally thought to be specific to placenta, it can also exist in other tissues, and it may play a role in the transport of methotrexate in synovial macrophages in rheumatoid arthritis patients. Multiple transcript variants that encode the same protein have been found for this gene. |
Product name: | Human FOLR2 Recombinant Protein (hFc Tag) |
Synonyms: | BETA-HFR; FBP; FBP/PL-1; FR-BETA; FR-P3; FRbeta |
Type: | protein |
Size: | 50 µg |
Name: | FOLR2 |
Origin: | Human |
Source: | HEK293 |
Protein Type: | Recombinant |
Application: | Contact Technical Support |
Purity: | Contact Technical Support |
Purification: | affinity purification |
Format: | Lyophilized |
Conjugate: | C-Human Fc |
Storage: | Store at -80°C for 12 months (Avoid repeated freezing and thawing) |
Usage: | Research use only |
Buffer: | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization. |
Reconstitution: | Reconstitute with deionized water |
Sequence: | FOLR2(Thr17-His228 )+hFc(Glu99-Ala330) |
Gene ID: | |
Uniprot: | P14207 |
Molecular Weight: | 48.84 kDa |