Growth Factors & Cytokines Recombinant Proteins
Human FLT3LG/Flt3 Ligand Recombinant Protein (RPES4206)
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- SKU:
- RPES4206
- Product Type:
- Recombinant Protein
- Species:
- Human
- Research Area:
- Growth Factors & Cytokines
Description
system_update_altDatasheet
Human FLT3LG/Flt3 Ligand Recombinant Protein
Fms-Related Tyrosine Kinase 3 Ligand (FLT3LG) is a hematopoietic four helical bundle cytokine. Mature human Flt-3 Ligand consists of a extracellular domain (ECD) with a cytokine-like domain and a juxtamembrane tether region, a transmembrane segment, and a cytoplasmic tail. Human and mouse Flt-3 Ligand show cross-species activity. Flt-3 Ligand is expressed as a noncovalently-linked dimer by T cells and bone marrow and thymic fibroblasts.It is structurally homologous to stem cell factor (SCF) and colony stimulating facor 1 (CSF-1). In synergy with other growth factors, Flt3 ligand stimulates the proliferation and differentiation of various blood cell progenitors by activiation of Flt 3 receptor.
| Product Name: | Human FLT3LG/Flt3 Ligand Recombinant Protein (RPES4206) |
| Product Code: | RPES4206 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | Human Cells |
| Synonyms: | Fms-Felated Tyrosine Kinase 3 Ligand, Flt3 Ligand, Flt3L, SL Cytokine, FLT3LG |
| Accession: | P49771 |
| Sequence: | Thr 27-Pro184 |
| Fusion tag: | C-6His |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Human Fms-like Tyrosine Kinase 3 Ligand is produced by our Mammalian expression system and the target gene encoding Thr27-Pro184 is expressed with a 6His tag at the C-terminus. |
| Purity: | > 95 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 18.9 kDa |
| AP Mol Mass: | 24-32 kDa |
| Formulation: | Lyophilized from a 0.2 µm filtered solution of 20mM TrisHCl?pH8.0. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
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