Human FKBP51 ELISA Kit

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SKU:
HUFI00845
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
Q13451
Sensitivity:
0.094ng/ml
Range:
0.156-10ng/ml
ELISA Type:
Sandwich
Synonyms:
FKBP51, FKBP5, Dit1, FKBP54, Ptg-10, 51 kDa FKBP, 54 kDa progesterone receptor-associated immunophilin, Androgen-regulated protein 6, FF1 antigen, FK506 binding protein 5, FK506-binding protein 5, FKBP-5, FKBP-51, HSP90-binding immunophilin, p54, pep
Reactivity:
Human
Research Area:
Signal Transduction

Description

Human FKBP51 ELISA Kit

FKBP5 belongs to the immunophilin protein family, which is important for immunoregulation and basic cellular processes linked to protein folding and trafficking. This prolyl isomerase binds FK506 and rapamycin, two immunosuppressants. FKBP5 has been shown to block calcineurin activity. It also has a function in mature hetero-oligomeric progesterone receptor complexes, as well as the 90 kD heat shock protein and P23 protein. Polyadenylation of this gene has been discovered in several locations. Major Depressive Disorder and Asthma are two examples of diseases influenced by FKBP5. MECP2 and associated Rett Syndrome, as well as PI3K / Akt Signaling are among the pathways affected by this protein.

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