Human FGFR5/FGFRL1 Recombinant Protein (RPES3737)

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SKU:
RPES3737
Product Type:
Recombinant Protein
Species:
Human

Description

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Human FGFR5/FGFRL1 Recombinant Protein

Fibroblast Growth Factor Receptor-Like 1 (FGFRL1) is a single-pass type I membrane protein that belongs to the FGF receptor family. The mature human FGFRL1 consists of a 354 amino acid extracellular domain (ECD) with 3 Ig-like C2-type domains, a 21 amino acid transmembrane segment, and a 134 amino acid cytoplasmic domain. FGFR1 expressed in various tissues, preferentially in cartilaginous tissues and pancreas. It highly expressed in the liver, kidney, heart, brain and skeletal muscle, weakly expressed in the lung, small intestine and spleen. FGFRL1 has a negative effect on cell proliferation.

Product Name:Human FGFR5/FGFRL1 Recombinant Protein (RPES3737)
Product Code:RPES3737
Size:10µg
Species:Human
Expressed Host:Human Cells
Synonyms:Fibroblast Growth Factor Receptor-Like 1, FGF Receptor-Like Protein 1, FGF Homologous Factor Receptor, FGFR-Like Protein, Fibroblast Growth Factor Receptor 5, FGFR-5, FGFRL1, FGFR5, FHFR
Accession:Q8N441
Sequence:Ala25-Pro378
Fusion tag:C-6His
Activity:Immobilized Human FGFb(Cat: PKSH032437) at 2µg/ml(100 ?l/well) can bind Human FGFRL1-His. The ED50 of Human FGFRL1-His is 0.0345 ug/ml.
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Human Fibroblast Growth Factor Receptor-Like 1 is produced by our Mammalian expression system and the target gene encoding Ala25-Pro378 is expressed with a 6His tag at the C-terminus.
Purity:> 95 % as determined by reducing SDS-PAGE.
Mol Mass:39.9 kDa
AP Mol Mass:40 kDa
Formulation:Lyophilized from a 0.2 µm filtered solution of 20mM TrisHCl, 150mM NaCl, pH 8.0.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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