Growth Factors & Cytokines Recombinant Proteins
Human FGF/FGFa Recombinant Protein (RPES3780)
- SKU:
- RPES3780
- Product Type:
- Recombinant Protein
- Species:
- Human
- Research Area:
- Growth Factors & Cytokines
Description
Human FGF/FGFa Recombinant Protein
The function of FGF acidic (ECGF/FGF-1/HBGF-1) is a non-glycosylated heparin binding growth factor that is found in the brain, kidney, retina, smooth muscle cells, bone matrix, osteoblasts, astrocytes, and endothelial cells. It is a mitogenic protein that is produced by many cell types, including mesodermal, ectodermal, and endodermal cells, and stimulates the growth of cells from these three layers. The presence of heparan sulfate is required for FGF receptors to be activated. The intracellular FGF acidic is transported to the nucleus, where it is phosphorylated by nuclear PKC delta, then exported to the cytosol dephosphorylated, and broken down. Intracellular FGF acidic inhibits p53 function and proapoptotic signaling. Human FGF/FGFa Recombinant Protein is a highly pure recombinant protein developed by Assay Genie for use in a range of applications.
| Product Name: | Human FGF/FGFa Recombinant Protein (RPES3780) |
| Product Code: | RPES3780 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | E.coli |
| Synonyms: | Fibroblast Growth Factor 1, FGF-1, Acidic Fibroblast Growth Factor, aFGF, Endothelial Cell Growth Factor, ECGFHeparin-Binding Growth Factor 1, HBGF-1, FGF1, FGFA |
| Accession: | P05230 |
| Sequence: | Ala2-Asp155 |
| Fusion tag: | |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Human Fibroblast growth factor 1/Fibroblast Growth Factor Acidic is produced by our E.coli expression system and the target gene encoding Ala2-Asp155 is expressed. |
| Purity: | > 95 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 17.3 kDa |
| AP Mol Mass: | 17 kDa |
| Formulation: | Lyophilized from a 0.2 µm filtered solution of PBS; pH 7.4. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
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