Human FEM1A ELISA Kit

(No reviews yet) Write a Review
SKU:
HUFI01958
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
Q9BSK4
Sensitivity:
0.188ng/ml
Range:
0.313-20ng/ml
ELISA Type:
Sandwich
Synonyms:
FEM1A, FEM1a, FEM1-alpha, Prostaglandin E receptor 4-associated protein, FEM1A, EPRAP
Reactivity:
Human
Research Area:
Signal Transduction

Description

Human FEM1A ELISA

FEM1A (Fem-1 Homolog A) belongs to the family of adhesion and connexin (gap junction) proteins. FEM1A is primarily expressed in endothelial cells and monocytes/macrophages, but also in adipocytes, skeletal muscle cells and brain astrocytes. FEM1A regulates angiogenesis and inflammatory processes by interacting with ZFYVE9 through its intracellular PDZ domain and with ITGB5 through its SH3 domain. FEM1A may also play a role in carcinogenesis. Mutations in FEM1A are associated with coronary artery disease (CAD), myocardial infarction (MI) and peripheral artery disease (PAD).

View AllClose

0 Reviews

View AllClose