Immunology Recombinant Proteins

Human FCGR1A/CD64 Recombinant Protein (RPES2238)

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RPES2238

Description

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Human FCGR1A/CD64 Recombinant Protein

CD64 (Fc?RI), one of the Fc receptors for IgG, is a membrane glycoprotein that mediates endocytosis, phagocytosis, antibody-dependent cellular cytotoxicity, cytokine release, and superoxide production. CD64 is also structurally distinct, containing an extracellular Ig-interactive region of three Ig-like domains in contrast to the two domains of the low affinity receptors Fc?RII and Fc?RIII. It is normally expressed on the surfaces of monocytes and macrophages.

Product Name:Human FCGR1A/CD64 Recombinant Protein (RPES2238)
Product Code:RPES2238
Size:10µg
Species:Human
Expressed Host:Human Cells
Synonyms:Ig gamma-4 chain C region,IgG4 Fc
Accession:P12314
Sequence:Gln16-Pro288
Fusion tag:C-His
Activity:Immobilized Human SIgG1-Fc(Cat: PKSH032558) at 2µg/ml(100 ?l/well) can bind Human CD64-His(Cat: PKSM041277). The ED50 of Human CD64-His is 0.05ug/ml .
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Human FCGR1A is produced by our Mammalian expression system and the target gene encoding Gln16-Pro288 is expressed with a 6His tag at the C-terminus.
Purity:> 95% as determined by reducing SDS-PAGE.
Mol Mass:31.7 kDa
AP Mol Mass:50-70 kDa
Formulation:Lyophilized from a 0.2 µm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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Additional Information

Product Type:
Recombinant Protein
Species:
Human
Research Area:
Immunology
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