Immunology Recombinant Proteins
Human FCGR1A/CD64 Recombinant Protein (RPES2238)
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- SKU:
- RPES2238
- Product Type:
- Recombinant Protein
- Species:
- Human
- Research Area:
- Immunology
Description
system_update_altDatasheet
Human FCGR1A/CD64 Recombinant Protein
CD64 (Fc?RI), one of the Fc receptors for IgG, is a membrane glycoprotein that mediates endocytosis, phagocytosis, antibody-dependent cellular cytotoxicity, cytokine release, and superoxide production. CD64 is also structurally distinct, containing an extracellular Ig-interactive region of three Ig-like domains in contrast to the two domains of the low affinity receptors Fc?RII and Fc?RIII. It is normally expressed on the surfaces of monocytes and macrophages.
| Product Name: | Human FCGR1A/CD64 Recombinant Protein (RPES2238) |
| Product Code: | RPES2238 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | Human Cells |
| Synonyms: | Ig gamma-4 chain C region,IgG4 Fc |
| Accession: | P12314 |
| Sequence: | Gln16-Pro288 |
| Fusion tag: | C-His |
| Activity: | Immobilized Human SIgG1-Fc(Cat: PKSH032558) at 2µg/ml(100 ?l/well) can bind Human CD64-His(Cat: PKSM041277). The ED50 of Human CD64-His is 0.05ug/ml . |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Human FCGR1A is produced by our Mammalian expression system and the target gene encoding Gln16-Pro288 is expressed with a 6His tag at the C-terminus. |
| Purity: | > 95% as determined by reducing SDS-PAGE. |
| Mol Mass: | 31.7 kDa |
| AP Mol Mass: | 50-70 kDa |
| Formulation: | Lyophilized from a 0.2 µm filtered solution of 20mM PB, 150mM NaCl, pH 7.4. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
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