Human FBLN4 / Fibulin 4 ELISA Kit

(No reviews yet) Write a Review
SKU:
HUFI02447
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
O95967
Sensitivity:
1.875ng/ml
Range:
3.125-200ng/ml
ELISA Type:
Sandwich
Synonyms:
FBLN4
Reactivity:
Human
Research Area:
Cell Biology

Description

Human FBLN4 / Fibulin 4 ELISA

FBLN4 (Fibulin 4) also known as EFEMP2 (EGF Containing Fibulin Extracellular Matrix Protein 2) contain four EGF2 domains and six calcium-binding EGF2 domains. Many extracellular matrix proteins have variations of the epidermal growth factor (EGF) domain and are involved in a wide range of functions, including blood coagulation, complement activation, and cell fate determination during development. The genes FBLN4/EFEMP2 are required for the development of elastic fibres and connective tissue. An autosomal recessive cutis laxa syndrome is caused by abnormalities in FBLN4/EFEMP2. Cutis laxa (autosomal recessive), type Ib and autosomal recessive cutis laxa type I are examples of disorders associated with FBLN4/EFEMP2. Integrin Pathway and ERK Signaling are two of the many FBLN4/EFEMP2 pathways. Calcium ion binding and extracellular matrix structural components are two of the GO annotations associated with FBLN4/EFEMP2. EFEMP1 is a crucial paralog of FBLN4/EFEMP2.

View AllClose

0 Reviews

View AllClose