Human FAM49B Recombinant Protein (RPPB3512)

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RPPB3512

Description

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Product Name:Human FAM49B Recombinant Protein
Product Code:RPPB3512
Size:20µg
Species:Human
Target:FAM49B
Synonyms:BM-009, L1, Protein FAM49B, FAM49B.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered colorless solution.
Formulation:FAM49B protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH8.0), 10% glycerol, 0.1M NaCl and 1mM DTT.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 90% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MGSMGNLLKV LTCTDLEQGP NFFLDFENAQ PTESEKEIYN QVNVVLKDAE GILEDLQSYR GAGHEIREAI QHPADEKLQE KAWGAVVPLV GKLKKFYEFS QRLEAALRGL LGALTSTPYS PTQHLEREQA LAKQFAEILH FTLRFDELKM TNPAIQNDFS YYRRTLSRMR INNVPAEGEN EVNNELANRM SLFYAEATPM LKTLSDATTK FVSENKNLPI ENTTDCLSTM ASVCRVMLET PEYRSRFTNE ETVSFCLRVM VGVIILYDHV HPVGAFAKTS KIDMKGCIKV LKDQPPNSVE GLLNALRYTT KHLNDETTSK QIKSMLQ

Family with Sequence Similarity 49, Member B (FAM49B) is a member of the FAM49 family. In the latest genome-wide transcriptional analysis, a gene signature was identified for multiple sclerosis (MS), which reverted back to normal during pregnancy. The reversion was mostly evident for seven genes: SOCS2, TNFAIP3, NR4A2, CXCR4, POLR2J, FAM49B, and STAG3L1, most of which are negative regulators of inflammation.

FAM49B Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 347amino acids (1-324 a.a) and having a molecular mass of 39.1kDa. FAM49B is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

UniProt Protein Function:
UniProt Protein Details:
NCBI Summary:
UniProt Code:Q9NUQ9
NCBI GenInfo Identifier:42734438
NCBI Gene ID:51571
NCBI Accession:NP_057707
UniProt Secondary Accession:Q9NUQ9,Q96AZ5, Q9NW21, Q9NZE7
UniProt Related Accession:Q9NUQ9
Molecular Weight:39.1 kDa (347aa) confirmed by MALDI-TOF
NCBI Full Name:protein FAM49B isoform 1
NCBI Synonym Full Names:family with sequence similarity 49 member B
NCBI Official Symbol:FAM49B��
NCBI Official Synonym Symbols:L1; BM-009��
NCBI Protein Information:protein FAM49B
UniProt Protein Name:Protein FAM49B
UniProt Synonym Protein Names:L1
Protein Family:Protein
UniProt Gene Name:FAM49B��
UniProt Entry Name:
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Additional Information

Product Type:
Recombinant Protein
Species:
Human
Uniprot:
Q9NUQ9
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