Human FAM49B Recombinant Protein (RPPB3512)
- SKU:
- RPPB3512
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- Q9NUQ9
Description
| Product Name: | Human FAM49B Recombinant Protein |
| Product Code: | RPPB3512 |
| Size: | 20µg |
| Species: | Human |
| Target: | FAM49B |
| Synonyms: | BM-009, L1, Protein FAM49B, FAM49B. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | FAM49B protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH8.0), 10% glycerol, 0.1M NaCl and 1mM DTT. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 90% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSMGNLLKV LTCTDLEQGP NFFLDFENAQ PTESEKEIYN QVNVVLKDAE GILEDLQSYR GAGHEIREAI QHPADEKLQE KAWGAVVPLV GKLKKFYEFS QRLEAALRGL LGALTSTPYS PTQHLEREQA LAKQFAEILH FTLRFDELKM TNPAIQNDFS YYRRTLSRMR INNVPAEGEN EVNNELANRM SLFYAEATPM LKTLSDATTK FVSENKNLPI ENTTDCLSTM ASVCRVMLET PEYRSRFTNE ETVSFCLRVM VGVIILYDHV HPVGAFAKTS KIDMKGCIKV LKDQPPNSVE GLLNALRYTT KHLNDETTSK QIKSMLQ |
Family with Sequence Similarity 49, Member B (FAM49B) is a member of the FAM49 family. In the latest genome-wide transcriptional analysis, a gene signature was identified for multiple sclerosis (MS), which reverted back to normal during pregnancy. The reversion was mostly evident for seven genes: SOCS2, TNFAIP3, NR4A2, CXCR4, POLR2J, FAM49B, and STAG3L1, most of which are negative regulators of inflammation.
FAM49B Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 347amino acids (1-324 a.a) and having a molecular mass of 39.1kDa. FAM49B is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q9NUQ9 |
| NCBI GenInfo Identifier: | 42734438 |
| NCBI Gene ID: | 51571 |
| NCBI Accession: | NP_057707 |
| UniProt Secondary Accession: | Q9NUQ9,Q96AZ5, Q9NW21, Q9NZE7 |
| UniProt Related Accession: | Q9NUQ9 |
| Molecular Weight: | 39.1 kDa (347aa) confirmed by MALDI-TOF |
| NCBI Full Name: | protein FAM49B isoform 1 |
| NCBI Synonym Full Names: | family with sequence similarity 49 member B |
| NCBI Official Symbol: | FAM49B�� |
| NCBI Official Synonym Symbols: | L1; BM-009�� |
| NCBI Protein Information: | protein FAM49B |
| UniProt Protein Name: | Protein FAM49B |
| UniProt Synonym Protein Names: | L1 |
| Protein Family: | Protein |
| UniProt Gene Name: | FAM49B�� |
| UniProt Entry Name: |
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