Human FAM3B Recombinant Protein (RPPB3509)
- SKU:
- RPPB3509
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- P58499
Description
| Product Name: | Human FAM3B Recombinant Protein |
| Product Code: | RPPB3509 |
| Size: | 10µg |
| Species: | Human |
| Target: | FAM3B |
| Synonyms: | Family with Sequence Similarity 3 member B, C21orf11, C21orf76, Cytokine-like protein 2-21, ORF9, PANDER, PRED44, Chromosome 21 open reading frame 11, Pancreatic-derived factor. |
| Source: | Escherichia Coli |
| Formulation: | FAM3B Human was filtered (0.4�m) and lyophilized from 0.5mg/ml supplied in 20mM TRIS, 50mM NaCl, pH 7.5 |
| Solubility: | Add deionized water to prepare a working stock solution of 0.5 mg/ml and let the lyophilized pellet dissolve completely. Product is not sterile! Please filter the product by an appropriate sterile filter before using it in the cell culture. |
| Stability: | Store lyophilized FAM3B uman at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted FAM3B an be stored at 4°C for a limited period of time; it does not show any change after two weeks at 4°C. |
| Purity: | Greater than 90% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MKHHHHHHAS ELIPDAPLSS AAYSIRSIGE RPVLKAPVPK RQKCDHWTPC PSDTYAYRLL SGGGRSKYAK ICFEDNLLMG EQLGNVARGI NIAIVNYVTG NVTATRCFDM YEGDNSGPMT KFIQSAAPKS LLFMVTYDDG STRLNNDAKN AIEALGSKEI RNMKFRSSWV FIAAKGLELP SEIQREKINH SDAKNNRYSG WPAEIQIEGC IPKERS |
FAM3B Protein induces apoptosis of alpha and beta cells in a quantity and time dependent way.
FAM3B Protein is a 24.1 kDa protein containing 216 amino acids fused to a 10 aa N-Terminal His-tag
| UniProt Protein Function: | FAM3B: Induces apoptosis of alpha and beta cells in a dose- and time-dependent manner. Present in insulin secretory granules and likely cosecreted with insulin. Belongs to the FAM3 family. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Cytokine; Secreted; Apoptosis; Secreted, signal peptide; Nuclear envelope Chromosomal Location of Human Ortholog: 21q22.3 Cellular Component: extracellular space; extracellular region Molecular Function:cytokine activity Biological Process: insulin secretion; apoptosis |
| UniProt Code: | P58499 |
| NCBI GenInfo Identifier: | 23821535 |
| NCBI Gene ID: | 54097 |
| NCBI Accession: | P58499.2 |
| UniProt Related Accession: | P58499 |
| Molecular Weight: | 235 |
| NCBI Full Name: | Protein FAM3B |
| NCBI Synonym Full Names: | family with sequence similarity 3, member B |
| NCBI Official Symbol: | FAM3B�� |
| NCBI Official Synonym Symbols: | 2-21; ORF9; PANDER; PRED44; C21orf11; C21orf76�� |
| NCBI Protein Information: | protein FAM3B; D21M16SJHU19e; pancreatic derived factor; pancreatic-derived factor; cytokine-like protein 2-21 |
| UniProt Protein Name: | Protein FAM3B |
| UniProt Synonym Protein Names: | Cytokine-like protein 2-21; Pancreatic-derived factor; PANDER |
| Protein Family: | Protein |
| UniProt Gene Name: | FAM3B�� |
| UniProt Entry Name: | FAM3B_HUMAN |
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