Enzymes Recombinant Proteins

Human ETNK2 Recombinant Protein (RPPB5834)

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RPPB5834

Description

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Product Name:Human ETNK2 Recombinant Protein
Product Code:RPPB5834
Size:5µg
Species:Human
Target:ETNK2
Synonyms:Ethanolaminekinase-2
Source:Escherichia Coli
Physical Appearance:Sterile Filtered colorless solution.
Formulation:ETNK2 protein solution (0.25mg/ml) in Phosphate buffered saline (pH7.4), 10% glycerol and 1mM DTT.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 90.0% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MGSMAVPPSA PQPRASFHLR RHTPCPQCSW GMEEKAAASA SCREPPGPPRAAAVAYFGIS VDPDDILPGA LRLIQELRPH WKPEQVRTKR FTDGITNKLV ACYVEEDMQD CVLVRVYGERTELLVDRENE VRNFQLLRAH SCAPKLYCTF QNGLCYEYMQ GVALEPEHIR EPRLFRLIAL EMAKIHTIHANGSLPKPILW HKMHNYFTLV KNEINPSLSA DVPKVEVLER ELAWLKEHLS QLESPVVFCH NDLLCKNIIYDSIKGHVRFI DYEYAGYNYQ AFDIGNHFNE FAGVNEVDYC LYPARETQLQ WLHYYLQAQK GMAVTPREVQRLYVQVNKFA LASHFFWALW ALIQNQYSTI DFDFLRYAVI RFNQYFKVKP QASALEMPK

ETNK2 belongs to theethanolaminekinase family which catalyzes the 1st step of PtdEtn biosynthesis via the cytidine diphosphate.

ETNK2 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 409 amino acids (1-386 a.a) and having a molecular mass of 47.2kDa.ETNK2 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

UniProt Protein Function:ETNK2: Highly specific for ethanolamine phosphorylation. Does not have choline kinase activity. Belongs to the choline/ethanolamine kinase family. 3 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Lipid Metabolism - glycerophospholipid; Kinase, other; EC 2.7.1.82

Chromosomal Location of Human Ortholog: 1q32.1

Cellular Component: cytosol

Molecular Function:ethanolamine kinase activity

Biological Process: phosphatidylethanolamine biosynthetic process

NCBI Summary:The protein encoded by this gene is a member of choline/ethanolamine kinase family which catalyzes the first step of phosphatidylethanolamine (PtdEtn) biosynthesis via the cytidine diphosphate (CDP) ethanolamine pathway. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
UniProt Code:Q9NVF9
NCBI GenInfo Identifier:296439366
NCBI Gene ID:55224
NCBI Accession:Q9NVF9.3
UniProt Secondary Accession:Q9NVF9,Q5SXX5, Q68CK3, Q96G05, B7Z7K1,
UniProt Related Accession:Q9NVF9
Molecular Weight:40,009 Da
NCBI Full Name:Ethanolamine kinase 2
NCBI Synonym Full Names:ethanolamine kinase 2
NCBI Official Symbol:ETNK2��
NCBI Official Synonym Symbols:EKI2; HMFT1716��
NCBI Protein Information:ethanolamine kinase 2
UniProt Protein Name:Ethanolamine kinase 2
UniProt Synonym Protein Names:Ethanolamine kinase-like protein
Protein Family:Ethanolamine kinase
UniProt Gene Name:ETNK2��
UniProt Entry Name:EKI2_HUMAN
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Additional Information

Product Type:
Recombinant Protein
Species:
Human
Uniprot:
Q9NVF9
Research Area:
Enzymes
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