Human ERP27 Recombinant Protein (RPPB3464)
- SKU:
- RPPB3464
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- Q96DN0
Description
| Product Name: | Human ERP27 Recombinant Protein |
| Product Code: | RPPB3464 |
| Size: | 10µg |
| Species: | Human |
| Target: | ERP27 |
| Synonyms: | Endoplasmic reticulum resident protein 27, ER protein 27, ERp27, ERP27, PDIA8, C12orf46, FLJ32115. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | The ERP27 solution (1mg/ml) contains 20mM Tris buffer (pH 8.0), 10% glycerol and 1mM DTT. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.�For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 90.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MEVEKSSDGP GAAQEPTWLT DVPAAMEFIA ATEVAVIGFF QDLEIPAVPI LHSMVQKFPG VSFGISTDSE VLTHYNITGN TICLFRLVDN EQLNLEDEDI ESIDATKLSR FIEINSLHMV TEYNPVTVIG LFNSVIQIHL LLIMNKASPE YEENMHRYQK AAKLFQGKIL FILVDSGMKE NGKVISFFKL KESQLPALAI YQTLDDEWDT LPTAEVSVEH VQNFCDGFLS GKLLKENRES EGKTPKVEL |
Endoplasmic reticulum protein 27kDa (ERP27) is a widely expressed protein which localizes to the ER and may act as a protease, protein disulfide isomerase, thiol-disulfide oxidase or phospholipase. ERP27 doesn�t contain a CXXC active site motif indicating that it is a catalytically redox-inactive member of the protein disulfide isomerase family.
ERP27 Human Recombinant fused with a 21 amino acid His tag at N-terminus produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 269 amino acids (26-273 a.a.) and having a molecular mass of 30kDa. The ERP27 is purified by proprietary chromatographic techniques.
| UniProt Protein Function: | ERP27: Belongs to the protein disulfide isomerase family. Interacts with PDIA3. Binds somatostatin-14 via hydrophobic interactions |
| UniProt Protein Details: | Protein type:Secreted, signal peptide; Secreted Chromosomal Location of Human Ortholog: 12p12.3 Cellular Component: endoplasmic reticulum Molecular Function:protein binding; protein disulfide isomerase activity Biological Process: protein folding |
| NCBI Summary: | ERP27 is a noncatalytic member of the protein disulfide isomerase (PDI; see MIM 608012) family of endoplasmic reticulum (ER) proteins (Alanen et al., 2006 [PubMed 16940051]).[supplied by OMIM, Mar 2008] |
| UniProt Code: | Q96DN0 |
| NCBI GenInfo Identifier: | 74731474 |
| NCBI Gene ID: | 121506 |
| NCBI Accession: | Q96DN0.1 |
| UniProt Related Accession: | Q96DN0 |
| Molecular Weight: | 30,480 Da |
| NCBI Full Name: | Endoplasmic reticulum resident protein 27 |
| NCBI Synonym Full Names: | endoplasmic reticulum protein 27 |
| NCBI Official Symbol: | ERP27�� |
| NCBI Official Synonym Symbols: | PDIA8; C12orf46�� |
| NCBI Protein Information: | endoplasmic reticulum resident protein 27 |
| UniProt Protein Name: | Endoplasmic reticulum resident protein 27 |
| Protein Family: | Endoplasmic reticulum resident protein |
| UniProt Gene Name: | ERP27�� |
| UniProt Entry Name: | ERP27_HUMAN |
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