Developmental Biology Recombinant Proteins
Human Ephrin-A5/EFNA5 Recombinant Protein (RPES3064)
- SKU:
- RPES3064
- Product Type:
- Recombinant Protein
- Species:
- Human
- Research Area:
- Developmental Biology
Description
Human Ephrin-A5/EFNA5 Recombinant Protein
Ephrin-A5 (EFNA5) belongs to the ephrin family,contains 1 ephrin RBD (ephrin receptor-binding) domain. Ephrin-A5 is a cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. It binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The interaction of EFNA5 with EPHA5 also mediates communication between pancreatic islet cells to regulate glucose-stimulated insulin secretion. Cognate/functional ligand for EPHA7, their interaction regulates brain development modulating cell-cell adhesion and repulsion.
| Product Name: | Human Ephrin-A5/EFNA5 Recombinant Protein (RPES3064) |
| Product Code: | RPES3064 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | Human Cells |
| Synonyms: | Ephrin-A5,EPLG7, LERK7,EFNA5,LERK-7,EPH-related receptor tyrosine kinase ligand 7,AL-1 |
| Accession: | P52803 |
| Sequence: | Gln21-Asn203 |
| Fusion tag: | C-Fc |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Human Ephrin-A5 is produced by our Mammalian expression system and the target gene encoding Gln21-Asn203 is expressed with a Fc tag at the C-terminus. |
| Purity: | > 95 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 48.3 kDa |
| AP Mol Mass: | 55-60 kDa |
| Formulation: | Lyophilized from a 0.2 µm filtered solution of PBS, pH7.4. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
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